Effect of the Newhints home-visits intervention on neonatal mortality rate and care practices in Ghana: a cluster randomised controlled trial

Economic evaluation of neonatal care packages in a cluster-randomized controlled trial in Sylhet, Bangladesh

“…38 In Ghana, recent findings from the Newhints home-visits intervention also indicate significant reductions in neonatal mortality. 39 In a meta-analysis of home-visit strategies in sub-Saharan Africa and South Asia -which included data from Sylhet and two other South Asian trials -a 12% (95% CI: 5-18) reduction in neonatal mortality was reported as the summary estimate of the impact of the implementation of such strategies.…”

Engagement of the Community, Traditional Leaders, and Public Health System in the Design and Implementation of a Large Community-Based, Cluster-Randomized Trial of Umbilical Cord Care in Zambia

“…This low rate compares favorably to chlorhexidine application trials conducted in south Asia (5% lost to follow-up in Bangladesh, and 2.5% lost to follow-up in Nepal) and newborn health trials in Africa. 7,8,22,23 Structural barriers. In Zambia, like many African countries, rural communities are widely dispersed, and families often travel great distances to reach primary health centers.…”

Clinical trials in Ghana: evolution and current landscape

“…There have also been several reproductive health-related trials, 62,63 as well as trials focused on improving newborn survival. 64,65 Notably, the only reported trial of artemisinin combination therapy for malaria treatment in Sickle Cell Disease (SCD), has recently been reported 66 ( Figure 4). …”

“…69 Notable among recent trials is a study that evaluated home visits as a strategy to improve neonatal survival, 65 within which was nested trial which showed that home visits also influenced uptake of skin-to-skin care among low birth-weight infants in rural areas and on neonatal survival. 70 In relation to other childhood illness was a study that evaluated immediate versus delayed (by one hour) application of Continuous Positive Airways Pressure (CPAP) procedure for childhood acute respiratory distress that showed that immediate CPAP administration resulted in significant decrease in respiratory rate.…”