1998
DOI: 10.1530/eje.0.1390387
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Effect of the somatostatin analog octreotide on gastric mucosal function and histology during 3 months of preoperative treatment in patients with acromegaly

Abstract: Objective: To study the effects of the somatostatin analog octreotide on gastric mucosal function and histology during short-term (3 months) preoperative treatment in patients with acromegaly.

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Cited by 6 publications
(2 citation statements)
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“…Together with a direct inhibitory effect at the parietal cell of the gastric mucosa, gastric acid—and probably intrinsic factor secretion—is reduced. Thus there is an increased risk of chronic gastritis and, with long-term therapy, a decline of the vitamin B12 concentration [97, 98]. This may be compensated by a monthly intramuscular injection of cyanocobalamin.…”
Section: Options For Medical Therapymentioning
confidence: 99%
“…Together with a direct inhibitory effect at the parietal cell of the gastric mucosa, gastric acid—and probably intrinsic factor secretion—is reduced. Thus there is an increased risk of chronic gastritis and, with long-term therapy, a decline of the vitamin B12 concentration [97, 98]. This may be compensated by a monthly intramuscular injection of cyanocobalamin.…”
Section: Options For Medical Therapymentioning
confidence: 99%
“…Prophylactic therapy with chenodeoxy-cholic acid and ursodeoxy-cholic acid may be able to prevent the occurrence of gallstone disease in patients on long-term SSA therapy. Serum vitamin B12 concentration may decline, possibly due to a direct inhibition of the intrinsic factor secretion at the parietal cell [52].…”
Section: Somatostatin Analogues (Ssa)mentioning
confidence: 99%