Effect of the Temperature of Tube Feeding on Gastric Motility in Monkeys

Effect of drink temperature on antropyloroduodenal motility and gastric electrical activity in humans.

“…Because of the significant impact of drink temperature on gastric emptying and antropyloric motility, this variable needs to be controlled for in studies of gastric motility and emptying. At first glance our findings seem to be at variance with two previous studies, one in monkeys and the other in humans, which found no effect of temperature on antral motility.5 6 However, the rate of heat transfer to the thermoreceptors in the gastric wall is dependent on both the intragastric volume and the temperature gradient, and the negative observations in previous studies may reflect both the lower volume of the liquid meals (100-250 ml) used and the narrower range of temperatures that was evaluated (5-39°C).5 6 Our observation that both the magnitude of antral suppression and stimulation of isolated pyloric pressure waves were greater with the cold (4°C) than the warm (50°C) drink is not unexpected, as the temperature gradient was larger with the cold drink (33°C v 13°C). It should also be recognised that in previous studies the methods used to measure gastric motility were suboptimal.5 6 For example, in the human studies, pressures were recorded at only one recording site in the antrum5 and in the animal study, antral motility was evaluated with o extraluminal strain gauge.6 These r could not give information about pyle tractions or the spatial patterning c contractions, variables that could be fully in our study because of the use of r closely spaced, manometric side holes the present study, previous studies5 6 control for the effect of the phase of ti digestive motor complex on gastric e and gastric motility.…”

Gastric emptying of liquid and solid meals at various temperatures

“…Some fundamental studies regarding the effect of meal temperature on gastric motility were carried out with animal models, and no close relationships between meal temperature and gastric emptying were found [5,20,21]. Some previous studies in humans showed that a cold meal induced an acceleration of gastric emptying [22,23] and a decrease in the myoelectrical frequency of gastric muscle [24], and cold enteral feeding was believed to be a possible cause of diarrhea [4].…”

“…Both the liquid and the solid test meals were ingested as fast as possible, within 1 min. Breath samples were collected before and after ingestion of the test meal: at baseline, at 5-min intervals during the first 20 min, at 10-min intervals during the next 40 min, and every 15 min for the last 60 min (0, 5,10,15,20,30,40,50,60,75,90,105, and 120 min). The concentration of 13 CO 2 in the collected breath samples was measured by isotope-selective nondispersive infrared spectrometry (UBiT IR 300; Otsuka Electronics, Osaka, Japan).…”

“…On the other hand, other investigators reported that both colder and warmer meals showed accelerated gastric emptying compared with meals at body temperature [3]. It was also reported that meal temperature did not show any effects on antral motility [4,5]. Thus, even in this limited number of reports, conflicting findings regarding the relationship between food temperature and gastric emptying time were found.…”

Gastric Hypomotility in Chronic Upper Gastrointestinal Disease of Japanese Macaques (Macaca fuscata)

“…Laboratory primates are used as models of human gastrointestinal disease, but studies of gastrointestinal disease in primates are rare [5,9,15,17]. Gastrointestinal disease has been associated with 31-44% of the deaths reported in primate colonies [10].…”