Effect of the yellow passion fruit peel flour (Passiflora edulis f. flavicarpa deg.) in insulin sensitivity in type 2 diabetes mellitus patients

Abstract

BackgroundA study with the yellow passion fruit peel flour showed positive action in blood glucose control as therapies’ adjuvant in patients with type 2 diabetes mellitus. Therefore, we evaluated its effect on insulin sensitivity since there is a quest for studies that focus at better understanding of insulin resistance aspects in diabetic patients. Furthermore its relationship with chronic complications can also give good prospects for alternative treatments.MethodsA total of 43 type 2 diabetes volunteers (28 females and 15 males) ingested 30 g/day of the yellow passion fruit peel flour for two months. The levels of blood glucose and fasting insulin, HOMA index and glycated hemoglobin were measured for each patient before and after dietary supplementation.ResultsThere was a significant difference in the fasting blood glucose values (P = 0.000) and glycated hemoglobin (P = 0.032) after supplementation. It was also seen a reduction in HOMA IR (P = 0.005) in the supplemented group, however it was not observed changes in insulin values for females. HOMA beta (P = 0.000) showed significant increase in its values for the studied group.ConclusionsThe supplementation used decreased insulin resistance in type 2 diabetic patients, suggesting a positive action in blood glucose control as adjuvant therapy in conventional treatments.

Capacidade antioxidante e composição química da casca de maracujá (Passiflora edulis)

“…Estudos têm demonstrado que o consumo da casca do maracujá pode ajudar no tratamento coadjuvante do controle glicêmico, com diminuição signifi cativa na glicemia de jejum, hemoglobina glicada, índice HOMA IR e aumento no índice HOMA (QUEIROZ et al, 2012); assim como no controle lipêmico, promovendo redução do colesterol total e fração LDL (RAMOS et al, 2007). Além disso, estudo com modelo experimental demonstrou efeito anti-infl amatório, com diminuição do volume do edema, liberação de mieloperoxidase, infi ltração de neutrófi los e da expressão de TNF- e iNOS (SILVA et al, 2011).…”

The effect of flour from the rind of the yellow passion fruit on glycemic control of people with diabetes mellitus type 2: a randomized clinical trial

“…However, among these studies, only one adopted HbA1 C as an outcome, and all were based in self-controlled samples (studies of the ‘before and after’ type) [17, 18, 20]. …”

Can the consumption of Seeds, Leaves and Fruit Peels avoid the risk factors for Cardiovascular Disorders?

“…Studies have demonstrated the presence of a high concentration of soluble fibers, especially pectin, phenolic compounds, such as isoorientin, coumarin, cyanidin-3-the-glycoside, quercetin-3-O-glycoside and edulic acid, among other yellow flavonoids. The treatment of experimental models and humans with the flour or yellow passion fruit peel extract revealed antihypertensive, antioxidant and antihyperglycaemic effects, in addition to decreased insulin resistance and hypolipidemic activity (56,57,58,59,60,61) .…”