Effect of Thioglycolic Acid Instillation to Stop Hair Growth on the Urethral Mucosa after Urethroplasty with Hairy Skin in a Rat Model

Abstract

Objective: The aim of this study was to investigate the impact of thioglycolic acid on normal urethral mucosa. Methods: Twenty-four rats were used. Three control and three study groups were formed each consisting of 4 rats. Controls groups were given 0.9% NaCl and study groups received thioglycolic acid instillation. The groups were allocated according to the time of urethral resection and the number of thioglycolic acid instillations (2, 4 or 8 instillations). The urethras of the rats were resected and examined under a light microscope in control and study groups 1, 2 and 3 on days 15, 30 and 60. Results: There was no difference in the urethral mucosa of rats in the study or control groups, and no differences were found when the study groups were compared to each of the other groups at the microscopic level. Conclusion: The application of thioglycolic acid is an easy and inexpensive way of clearing urethral hair and does not cause pathological changes in the normal urethral mucosa.

Diode laser epilation of urethral hair follicles following urethroplasty

“…Fakat Neodymium: YAG lazer kullanımda lazerin kıl folliküllerini tahrip etmek için etkili doku derinliğinin sağlanabildiği ve başarılı olduğu bildirilmiştir. [2] Sunay ve arkadaşlarının [3] çalışmasında epilasyonda kullanılan tüy dökücü kremlerin içeriğinde de bulunan thioglycolic asit içeren sıvıyı ratlarda üretra instillasyonu şeklinde uygulamış ve serum fizyolojik verilen kontrol grubu ile karşılaştırılmış. Bu çalışmada her iki grup arasında üretral mukozal hasar açısından fark olmadığı ve tedavi maliyetinin çok düşük olduğu rapor edilmiş.…”