Effect of thrombin conjugation on hemostatic efficacy of PLGA mesh through reagent free surface modification

Lee, In Kyu; You, Su Jung; Yun, Young Jin; Kim, Jae Kwang; Yang, Dae Hyeok; Chun, Heung Jae; Ko, Jae-Hoon; Koh, Young-Joo

doi:10.1016/j.jiec.2022.10.049

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Biological Hemostatic Materials1

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2024

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Cited by 2 publications

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“…The good hemostatic properties were attributed to the hydrophilicity of the PLGA-THR sample surface and the increase in FX IIIa activity. The inflammatory response of THR-PLGA was significantly reduced compared to Vicryl and TachoSil …”

Section: Biological Hemostatic Materialsmentioning

confidence: 93%

Recent Advances in Topical Hemostatic Materials

Liu,

Zhang,

Yao

et al. 2024

ACS Appl. Bio Mater.

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Untimely or improper treatment of traumatic bleeding may cause secondary injuries and even death. The traditional hemostatic modes can no longer meet requirements of coping with complicated bleeding emergencies. With scientific and technological advancements, a variety of topical hemostatic materials have been investigated involving inorganic, biological, polysaccharide, and carbonbased hemostatic materials. These materials have their respective merits and defects. In this work, the application and mechanism of the major hemostatic materials, especially some hemostatic nanomaterials with excellent adhesion, good biocompatibility, low toxicity, and high adsorption capacity, are summarized. In the future, it is the prospect to develop multifunctional hemostatic materials with hemostasis and antibacterial and anti-inflammatory properties for promoting wound healing.

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Section: Biological Hemostatic Materialsmentioning

confidence: 93%