Background::
The effects of thyroid hormone on patients hospitalized in coronary
intensive care units are still controversial. We retrospectively examined thyroid hormone levels
and their impact on cardiovascular morbidity in patients admitted to coronary intensive care
units.
Material and Methods::
A total of 208 (Female/Male; 47.1%/52.9%) patients without any history
of thyroid disease were enrolled and screened. Patients with specific heart disease and existing
thyroid hormone parameters were included in the study. Low triiodothyronine syndrome is
characterized by reduced serum total or free T3 (fT3) concentrations in normal free T4 (fT4)
and TSH levels.
Results::
The common diagnosis of the patients in the coronary care unit is acute coronary syndrome
(n=59, 28.2 %) and heart failure (n=46, 23.3%). Patients were divided into two groups
according to left ventricular ejection fraction percentages (LVEF ≤39% vs LVEF ≥40%). Plasma
fT3 levels were significantly correlated with low LVEF (≤39%) (p =0.002). fT3 (r=-0.183, p
=0.013) and hospitalization etiology (r=-0.161, p =0.023) were also the most critical parameters
affecting the length of hospitalization.
Conclusion::
Low fT3 was associated with reduced ejection fraction and prolonged hospitalization,
which may lead to potential morbidities in HF patients, which may be useful in risk stratification
and treatment strategies.