Effect of titin phosphorylation on degradation of titin from skeletal muscles

Wang, Ying; Li, Xin; Zhang, Dequan; Li, Zheng; Xu, Baocai; Zhu, Jie

doi:10.1016/j.fshw.2022.10.001

Cited by 2 publications

(1 citation statement)

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“…It has been demonstrated that a significant relevance was observed between textural loss and the degradation of myosin heavy chain (MHC) and actin (Ge et al ., 2018). In addition, titin (known as connectin, 3000 kDa) and nebulin (600–800 kDa) as giant myofibrillar proteins contribute to assembling and maintaining sarcomeres by associating with thick and thin filaments (Wang et al ., 2023). The proteolysis of titin and nebulin leads to the degradation of myofilaments and costameres, breaking the links between sarcomeres with sarcolemma (Yang et al ., 2019).…”

Section: Introductionmentioning

confidence: 99%

Action of structural proteins in textural deterioration of grass carp (Ctenopharyngodon idellus) fillets during refrigerated storage

Shen,

Zhong,

Xia

et al. 2024

Int J of Food Sci Tech

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SummaryTextural deterioration is a severe problem in fish industry. In order to study the role of structural proteins in refrigerated grass carp, myofibrillar proteins and collagen degradation were investigated at different stages. Results revealed that connective tissues of fish muscle disintegrated from day 1, failing to hold muscle myotomes together, with a decrease of shear force. Meanwhile, collagen solubility increased from day 1 and degradation of nebulin was observed after 3 days, while there was no obvious change in the bands of myosin heavy chain and actin. Furthermore, Pearson coefficient analysis revealed that insoluble collagen (ISC) and nebulin were significantly correlated with shear force. Negative correlation was established between drip loss and contributing factors (ISC, titin and nebulin). All results suggested that textural loss of post‐mortem grass carp fillets was mainly mediated by the degradation of collagen and to a lesser extent by myofibrillar proteins at the early storage.

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Section: Introductionmentioning

confidence: 99%