Effect of topical application of tetracaine on intraocular pressure in dogs: Preliminary results

Boillot, Thomas; Gauvin, Mathieu; Rosolen, Serge G.

doi:10.1016/j.jfo.2012.07.006

Cited by 7 publications

(8 citation statements)

References 18 publications

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“…On the other hand, Boillot et al . reported a decrease in canine IOP, and Sarchahi et al . reported a decrease in rabbit IOP following administration of topical anesthesia.…”

Section: Discussionmentioning

confidence: 93%

The effects of topical parasympatholytic drugs on pupil diameter and intraocular pressure in healthy dogs treated with 0.005% latanoprost

Kahane

Raskansky

Bdolah‐Abram

et al. 2015

Veterinary Ophthalmology

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“…On the other hand, Boillot et al . reported a decrease in canine IOP, and Sarchahi et al . reported a decrease in rabbit IOP following administration of topical anesthesia.…”

Section: Discussionmentioning

confidence: 93%

The effects of topical parasympatholytic drugs on pupil diameter and intraocular pressure in healthy dogs treated with 0.005% latanoprost

Kahane

Raskansky

Bdolah‐Abram

et al. 2015

Veterinary Ophthalmology

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“…One recent study showed that tropicamide increased IOP in dogs by 8.8 ± 4.0 mmHg by 35 minutes post‐treatment compared to pre‐treatment, 31 while another study showed that the majority (60%) of dogs displayed 5 mmHg or less in IOP change post‐mydriasis 32 . Topical anesthetics, on the other hand, tend to reduce IOP readings 27,33,34 . However, attempts were made to reduce the overall effect of these medications on individual tonometer readings by randomization of the order with which each tonometer was used, and all readings were obtained within 10 minutes from the time of topical anesthetic and mydriatic application.…”

Section: Discussionmentioning

confidence: 99%

The effect of central corneal thickness on intraocular pressure values using various tonometers in the dog

Guresh

Horvath

Gemensky-Metzler

et al. 2021

Veterinary Ophthalmology

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Objective To compare intraocular pressure readings from three different tonometers, the Tono‐Pen AVIA® (TP), TonoVet® (TV) and TonoVet Plus® (TV+) and to determine how measurements from each tonometer are affected by central corneal thickness (CCT). Animals Ninety dogs. Procedures Normal dogs and dogs with ocular disease were selected for study inclusion. Central corneal thickness measurements were gathered with the Pachette 4 ultrasonic pachymeter, and IOP measurements were gathered with the three tonometers in random order. ANOVA or Wilcoxon tests were utilized for overall group comparisons. Linear regression analyses were utilized to determine the association between IOP and CCT. Results When comparing tonometers to each other, for all dogs, readings from the TV+were significantly different compared to the TV (p = <.0001) and TP (p = <.0001); however, there was no significant difference between the TV and the TP (p = .999). Linear regression did not find any significant correlation between corneal thickness and IOP readings with any tonometer when looking at normal dogs or when including dogs with ocular abnormalities. Discussion This study did not find a significant correlation between an increase in CCT and increase in IOP reading in any tonometer comparison amongst normal and dogs with ocular abnormalities. The TV+produced consistently and significantly higher readings, but measurements did not exceed the expected IOP range in normal dogs. For consistency, the same tonometer should be used when monitoring IOP over time.

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“…6 Parchen et al reported a significant decrease in IOP in dogs 30 mins and 50 mins after tetracaine and proparacaine administration, respectively. 8 In a study by Boillot et al, 5 IOP decreased 1 min after tetracaine administration in the treated eye in dogs. 5 All these studies in dogs showed significant alterations in IOP at different time points.…”

Section: Discussionmentioning

confidence: 95%

“…8 In a study by Boillot et al, 5 IOP decreased 1 min after tetracaine administration in the treated eye in dogs. 5 All these studies in dogs showed significant alterations in IOP at different time points. Age, breed, time of measurements, variable corneal thickness and inter-observer difference were the possible reasons for the difference between these studies.…”

Section: Discussionmentioning

confidence: 95%

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Effect of topical 0.5% tetracaine hydrochloride on intraocular pressure in ophthalmologically normal cats

Faghihi

Rajaei

Ostadhasan

et al. 2021

Journal of Feline Medicine and Surgery

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Objectives The aim of this study was to assess the effect of topical tetracaine hydrochloride 0.5% on intraocular pressure (IOP) in ophthalmologically normal cats. Methods Twenty domestic shorthair cats (40 eyes) were used in this study. Each cat was randomly allocated to one of two groups (treatment or control). Baseline IOP (T0) was measured in each cat, and then one drop of tetracaine hydrochloride 0.5% or artificial tears was administered into a randomly chosen eye of each cat in the treatment and control groups, respectively. Repeat IOP measurements were performed at 2 mins (T2), 5 mins (T5), 15 mins (T15) and 30 mins (T30) with a rebound tonometer. Results Mean baseline IOP in all eyes was 20.6 ± 2.5 mmHg. After the unilateral administration of tetracaine, mean IOP decreased significantly in the treated eye at T2 ( P = 0.01). Mean IOP returned to baseline values at T15. The mean IOPs in the treated eyes at T0, T2, T5, T15 and T30 were 20.6 ± 3.3 mmHg, 18.2 ± 2.5 mmHg, 18.2 ± 3.4 mmHg, 20.2 ± 3.2 mmHg and 19.8 ± 2.7 mmHg, respectively. A significant difference in IOP was found at all time points between the tetracaine and control groups (P <0.03). Conclusions and relevance The results of the present study showed a statistically significant reduction in mean IOP 2 mins after the administration of tetracaine hydrochloride 0.5% in the treated eyes of the cats.

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Effect of topical application of tetracaine on intraocular pressure in dogs: Preliminary results

Cited by 7 publications

References 18 publications

The effects of topical parasympatholytic drugs on pupil diameter and intraocular pressure in healthy dogs treated with 0.005% latanoprost

The effects of topical parasympatholytic drugs on pupil diameter and intraocular pressure in healthy dogs treated with 0.005% latanoprost

The effect of central corneal thickness on intraocular pressure values using various tonometers in the dog

Effect of topical 0.5% tetracaine hydrochloride on intraocular pressure in ophthalmologically normal cats

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