Effect of topical fluoride applications on residual monomer release from resin-based restorative materials

Abstract

Background The effects of topical fluoride applications on the release of monomer ingredients from resin-based dental materials by immersion in various extraction solutions are unclear. The aim of this study was to determine the effect of topical fluorides (APF and NaF) on the elution of residual monomers (Bis-GMA, TEGDMA, UDMA, and HEMA) from resin-based materials. Methods Ninety specimens were prepared, 30 bulk-fill composite resin, 30 nanohybrid universal composite resin, and 30 polyacid-modified composite resin (compomer). These were randomly divided into three groups based on fluoride application procedures. Each specimen was kept in 75% ethanol solution, and residual monomers released from materials were analyzed using high-performance liquid chromatography (HPLC) after 10 min, 1 h, 24 h, and 30 days. The groups were compared using the Mann Whitney U and Kruskal Wallis tests. Measurements were analyzed using the Friedman and Wilcoxon signed-rank tests. Results Fluoride applications generally had no considerable effect on the amount of residual monomer released from resin-based restorative materials. The amount of monomer release after topical APF application was similar to the release in the control group and was lower than the release in the NaF group. The release of monomers from the resin-based material used in the study did not approach toxic levels at the applied time intervals. The compomer released lower amounts of monomer than other resin-based materials. Conclusions Fluoride applications do not increase monomer release from resin-based restorative materials. However, compomers should be employed by clinicians due to their lower monomer release compared to other resin restorative materials. The release of monomers from all the resin-based materials did not approach toxic levels at the applied time intervals.

Release Kinetics of Monomers from Dental Composites Containing Fluoride-Doped Calcium Phosphates

“…Several methodologies, including gas-liquid chromatography [ 40 , 41 ] and mass spectrometry [ 41 , 42 ], have been used to quantify the amount of residual monomer eluted from dental materials. Chromatographic methods such as HPLC seem to be a suitable approach for the reliable assessment of resin monomer released from resin composites [ 41 ]. The results of the current study provided significant insights into monomer release within the evaluated resin composites.…”

Alterations in Surface Gloss and Hardness of Direct Dental Resin Composites and Indirect CAD/CAM Composite Block after Single Application of Bifluorid 10 Varnish: An In Vitro Study

“…Chemical treatments or even preventive measures like fluoride varnish and other dental hygiene products can harm the surface of restorative materials [9,10]. They may have adverse effects on resin composites, like discoloration, surface erosion, reduced surface hardness, and the dissolving of inorganic fillers [11].…”

Mouthwashes: Surface Hardness and Accuracy of Dual-cured Visible Light-Cured Composite

“…However, few studies claimed that the microhardness value of composite depends on the material itself rather than the rinsing solutions, and alcohol-contain mouthwashes have no adverse effect on the composite material (32,33) . Few studies reported that an active ingredient in the mouthwashes like sodium fluoride may cause surface deterioration and reduction in the microhardness of composite (34,35) , also fluoride-containing mouthwashes can have an impact on the solubility of some composite restorative materials (17,36) . On the other hand, many studies stated conflicting results regarding the impact of chlorhexidine-based mouthwashes on composite material hardness (37)(38)(39) .…”