Effect of Transcatheter Aortic Valve Replacement on Right Ventricular Systolic Function: Systematic Review and Meta-analyses

Zahaf, Marwah; Basu, Sanjib

doi:10.4172/2155-9880.1000447

J Clin Exp Cardiolog

2016

DOI: 10.4172/2155-9880.1000447

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Effect of Transcatheter Aortic Valve Replacement on Right Ventricular Systolic Function: Systematic Review and Meta-analyses

Marwah Zahaf¹,

Sanjib Basu²

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Cited by 3 publications

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“…Zahaf et al demonstrated that surgical aortic valve replacement was associated with a worsening in RV function postoperatively, whereas no reduction in RV function was identified post-transcatheter aortic valve replacement. 7 This finding potentially has implications for surgical planning in symptomatic aortic stenosis patients with pre-existing RV dysfunction. Additionally, RV dysfunction is a well-described contributor to morbidity and mortality in the setting of LV assist device implantation, often complicating management strategies.…”

mentioning

confidence: 94%

The Right Ventricle: A Rags-to-Riches Story

Maus

2017

Journal of Cardiothoracic and Vascular Anesthesia

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mentioning

confidence: 94%

The Right Ventricle: A Rags-to-Riches Story

Maus

2017

Journal of Cardiothoracic and Vascular Anesthesia

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The Year in Perioperative Echocardiography: Selected Highlights From 2016

Khoche¹,

Ramsingh

Maus³

2017

Journal of Cardiothoracic and Vascular Anesthesia

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Prognostic Assessment of Right Ventricular Systolic Dysfunction on Post–Transcatheter Aortic Valve Replacement Short‐Term Outcomes: Systematic Review and Meta‐Analysis

Grevious

Fernandes

Annor

et al. 2020

JAHA

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Background Right ventricular systolic dysfunction ( RVSD ) is a known risk factor for adverse outcome in surgical aortic valve replacement. Transcatheter aortic valve replacement ( TAVR ), on the other hand, has been shown to be either beneficial or have no effect on right ventricular systolic function. However, the prognostic significance of RVSD on TAVR has not been clearly determined. We conducted a systematic review and meta‐analysis to define the impact of RVSD on outcomes in terms of 1‐year mortality in patients with severe aortic stenosis undergoing TAVR . Methods and Results An extensive literature review was performed, with an aim to identify clinical studies that focused on the prognosis and short‐term mortality of patients with severe symptomatic aortic stenosis who underwent TAVR . A total of 3166 patients from 8 selected studies were included. RVSD , as assessed with tricuspid annular plane systolic excursion, fractional area change or ejection fraction, was found to be a predictor of adverse procedural outcome after TAVR (hazard ratio, 1.31; 95% CI, 1.1–1.55; P =0.002). Overall, we found that RVSD did affect post‐ TAVR prognosis in 1‐year mortality rate. Conclusions Patients with severe, symptomatic aortic stenosis and concomitant severe RVSD have a poor 1‐year post‐ TAVR prognosis when compared with patients without RVSD . Right ventricular dilation and severe tricuspid regurgitation were associated with increased 1‐year morality post‐ TAVR and should be considered as independent risk factors. Further evaluations of long‐term morbidity, mortality, as well as sustained improvement in functional class and symptoms need to be conducted to determine the long‐term effects.

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Effect of Transcatheter Aortic Valve Replacement on Right Ventricular Systolic Function: Systematic Review and Meta-analyses

Cited by 3 publications

References 44 publications

The Right Ventricle: A Rags-to-Riches Story

The Right Ventricle: A Rags-to-Riches Story

The Year in Perioperative Echocardiography: Selected Highlights From 2016

Prognostic Assessment of Right Ventricular Systolic Dysfunction on Post–Transcatheter Aortic Valve Replacement Short‐Term Outcomes: Systematic Review and Meta‐Analysis

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