Effect of Trauma on Growth of Hair

Fn, Ghadially

doi:10.1038/181993a0

Cited by 19 publications

(9 citation statements)

References 9 publications

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“…Alternatively, the contribution of the lower HF stem cell compartment may be influenced by hair-cycle-dependent changes in the HF microenvironment. This may account for the observations that HFs are stimulated to enter anagen phase following wounding and wounds heal faster when inflicted close to anagen-phase hair follicles (Argyris, 1956;Ghadially, 1958;Zawacki and Jones, 1967).…”

Section: Skin Stem Cell Plasticity and Wound Repairmentioning

confidence: 97%

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

2010

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The epithelial lining of the intestine, stomach, and skin is continuously exposed to environmental assault, imposing a requirement for regular self-renewal. Resident adult stem cell populations drive this renewal, and much effort has been invested in revealing their identity. Reliable adult stem cell biomarkers would accelerate our understanding of stem cell roles in tissue homeostasis and cancer. Membrane-expressed markers would also facilitate isolation of these adult stem cell populations for exploitation of their regenerative potential. Here, we review recent advances in adult stem cell biology, highlighting the promise and pitfalls of the candidate biomarkers of the various stem cell populations.

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Section: Skin Stem Cell Plasticity and Wound Repairmentioning

confidence: 97%

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

2010

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“…The key factor is injury to the skin surface or to the hair follicle. Therefore, hair plucking, vigorous shaving or chemical exposure to depilatory agents were considered to induce anagen [33], whereas cutting the hair without causing injury to the skin does not [34]. However, plucking experiments and Monte Carlo simulations [35,36] indicate that hair removal is not always followed by the reset of the follicle to telogen or by a continuation of the anagen VI stage.…”

Section: Models and Simulationsmentioning

confidence: 99%

EEMCO Guidance for the Assessment of Hair Shedding and Alopecia

Pierard

Piérard-Franchimont

Marks

et al. 2004

Skin Pharmacol Physiol

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Knowledge of the hair follicle anatomy and the dynamics of hair cycling is substantial. Recognizing the anagen, catagen and telogen phases as well as teloptosis and the hair eclipse phenomenon clearly characterizes the typical hair chronobiology. Physiological modulators include hormones, neuromediators, miscellaneous biomolecules, seasons, micro-inflammation and ageing. For individuals who present with the complaint of increased hair shedding or alopecia, a host of evaluation techniques are available in addition to history, physical examination and laboratory assessment. Various clinical hair techniques can help in assessing the efficacy of drugs and cosmetics on hair growth. The methods are quite similar to those used to establish a definite diagnosis in dermatological practice. Great strides have been made during the recent decades in the methodology of hair growth trials in dermatology and cosmetology. Clinical evaluations benefit from a few additional specific techniques that enhance the perception of hair (re-) growth, shedding and alopecia. These assessments include the determination of hair patterning and density that may be helped by the ‘black-and-white felt’ examination. Daily hair counts, the ‘hair pull test’ and the ‘hair feathering test’ are also available. Instrumental methods provide reliable quantitative information that is useful if there are adequate controls. Some photographic methods, the trichogram, hair weighing and variants of the hair growth window technique including the phototrichogram, videotrichogram and tractio-phototrichogram provide insight into the complexities of hair cycling and shedding. Skin biopsy is indicated for diagnostic purposes, especially when the hair loss is accompanied by scarring.

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“…On the other hand, but still in support of the theory that excess hair growth only occurs where tissues are well oxygenated, Dodd & Cockett (1956) believe that there is a tendency for varicose veins to be associated with lack or loss of hair, assuming that varicose disease creates conditions of hypoxia. Perhaps the most interesting contribution is by Ghadially (1958) who found that during the quiescent phase of the hair growth cycle in the rabbit, a tuft of new hair would arise at the site of a small incision in a shaven area.…”

Section: Discussionmentioning

confidence: 99%

Localized hirsuties

Schraibman

1967

Postgraduate Medical Journal

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Effect of Trauma on Growth of Hair

Cited by 19 publications

References 9 publications

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

EEMCO Guidance for the Assessment of Hair Shedding and Alopecia

Localized hirsuties

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