Effect of treatment time on outcome of radiotherapy for oral tongue carcinoma

Treatment delays in oral cavity squamous cell carcinoma and association with survival

“…A strong body of evidence shows that prolonged radiation treatment is associated with worse locoregional control and survival in HNSCC [12][13][14][15] ; however, impact of other treatment time intervals is less conclusive. [16][17][18] According to the National Comprehensive Cancer Network guidelines, the preferred interval between resection and commencement of postoperative radiotherapy (RT) is 6 weeks or less.…”

Technical and Dosimetric Considerations in Multi-Isocenter Intensity Modulated Radiotherapy for Nasopharyngeal carcinoma with Small Multileaf Collimator

“…Increases in the treatment time are reported to influence local control of head-and-neck carcinomas treated with external beam radiotherapy. [22][23][24] Further influence of this complexity and longer delivery time caused by the increase of isocenter number in IMRT plans needs to be studied after a long follow-up of these nasopharyngeal carcinoma patients.…”

Cesium Implant for Tongue Carcinoma with a Thickness of 1.5 cm or More: Cases Successfully Treated with a Modified Manchester System

“…We have been using the Manchester System for the past 3 decades, although sometimes external radiation was also combined with cesium (Cs) brachytherapy. Hosokawa, et al2 has reported on the treatment results of combination therapy at our institute. The percent of patients with 5 year local control for T1 and T2 diseases were 92.6% and 62.7%, respectively 2.…”

“…Hosokawa, et al2 has reported on the treatment results of combination therapy at our institute. The percent of patients with 5 year local control for T1 and T2 diseases were 92.6% and 62.7%, respectively 2. The value for T1 disease was comparable with the results achieved at other institutions.…”

“…Surgeons hesitate in recommending a near hemiglossectomy particularly for young patients. This is because the procedures are to some extent associated with orocutaneous fistula, flap necrosis, dysphagia, and speech disturbance 2. Hence, treatments for tumors such as ours are controversial.…”