Effect of tumor necrosis factor-α on thein vitro synthesis of interleukin-8 by human monocytes and lymphocytes

Abstract

The addition of recombinant tumor necrosis factor or monoclonal antibodies to this factor into human monocyte culture does not change the synthesis of interleukin-8. By contrast, tumor necrosis factor induces the synthesis of interleukin-8 in human lymphocytes.