Effect of twelve-month physical exercise program on patients with osteoporotic vertebral fractures: a randomized, controlled trial

Евстигнеева, Л. П.; Lesnyak, Olga; Bultink, Irene E. M.; Lems, Willem F.; Kozhemyakina, E V; Negodaeva, Elena V.; Гусельникова, Г.А.; Belkin, Andrey

doi:10.1007/s00198-016-3560-4

Cited by 44 publications

(50 citation statements)

References 26 publications

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“…Wang and colleagues also reported a significant between‐group difference in favor of the intervention for self‐reported physical function using the ODI after 6 and 12 months. Finally, a recent study reported that the exercise intervention led to a significant improvement in some subscales of the QUALLEFO‐41 questionnaire, including jobs around the house subscale and mobility subscale, but no change in activities of daily living subscale . In summary, there is some evidence of small benefit in longer term follow‐up when it comes to self‐reported function/disability.…”

Section: The Efficacy and Safety Of Vertebral Augmentation: Task Forcmentioning

confidence: 98%

The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report

Ebeling

Åkesson

Bauer

et al. 2019

Journal of Bone and Mineral Research

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Vertebral augmentation is among the current standards of care to reduce pain in patients with vertebral fractures (VF), yet a lack of consensus regarding efficacy and safety of percutaneous vertebroplasty and kyphoplasty raises questions on what basis clinicians should choose one therapy over another. Given the lack of consensus in the field, the American Society for Bone and Mineral Research (ASBMR) leadership charged this Task Force to address key questions on the efficacy and safety of vertebral augmentation and other nonpharmacological approaches for the treatment of pain after VF. This report details the findings and recommendations of this Task Force. For patients with acutely painful VF, percutaneous vertebroplasty provides no demonstrable clinically significant benefit over placebo. Results did not differ according to duration of pain. There is also insufficient evidence to support kyphoplasty over nonsurgical management, percutaneous vertebroplasty, vertebral body stenting, or KIVA®. There is limited evidence to determine the risk of incident VF or serious adverse effects (AE) related to either percutaneous vertebroplasty or kyphoplasty. No recommendation can be made about harms, but they cannot be excluded. For patients with painful VF, it is unclear whether spinal bracing improves physical function, disability, or quality of life. Exercise may improve mobility and may reduce pain and fear of falling but does not reduce falls or fractures in individuals with VF. General and intervention-specific research recommendations stress the need to reduce study bias and address methodological flaws in study design and data collection. This includes the need for larger sample sizes, inclusion of a placebo control, more data on serious AE, and more research on nonpharmacologic interventions. Routine use of vertebral augmentation is not supported by current evidence. When it is offered, patients should be fully informed about the evidence. Anti-osteoporotic medications reduce the risk of subsequent vertebral fractures by 40-70%.

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Section: The Efficacy and Safety Of Vertebral Augmentation: Task Forcmentioning

confidence: 98%

The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report

Ebeling

Åkesson

Bauer

et al. 2019

Journal of Bone and Mineral Research

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“…Previous studies have reported the benefits of muscle strength exercise in the clinical management of patients with osteoporotic vertebral fractures. [14][15][16] We tried to start physical therapy as soon as possible to prevent disuse weakness.…”

Section: Discussionmentioning

confidence: 99%

The Association between Nutrition and the Functional Outcomes of Elderly Women with Acute Vertebral Compression Fractures

Otsuka

Tazawa

Ibe

et al. 2018

kmj

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Background: Vertebral compression fracture (VCF) is a major injury that occurs in elderly individuals. The aim of this study is to predict the functional outcomes of elderly female patients with acute VCF based on their nutritional status. Methods: A total of 69 female patients with acute VCF were included in the present study. The age, fracture location, body mass index, grasping power, the amount of the patientʼs daily nutritional intake, Mini-Mental State Examination (MMSE) score and nutritional status (determined from laboratory findings) were evaluated at the time of admission. After in-hospital rehabilitation, the patients were divided into two groups based on their motor Functional Independence Measure (mFIM) scores at the time of discharge. A multivariable logistic regression analysis was performed to identify factors that predicted the outcome. Results: The patients were divided into the high mFIM (score ≥ 79, n＝36) and the low mFIM (score＜79, n＝33) groups. The multivariate logistic regression analysis showed that the amount of the patient' s nutritional intake and the MMSE score were associated with the outcome. Conclusions: he cognitive status and the amount of the patient' s nutritional intake were associated with the prognosis of elderly women with acute VCF.

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“…BSE will be conducted with a computerized posturographic system for diagnosing balance and movement skills (Balance Master System NeuroCom; Natus Medical Inc., Pleasanton, CA) designed to objectively quantify balance and postural function of different origins, as described previously. [ 13 ] Briefly, subjects will be prepared by being introduced to the supported standing position with the objective of looking for a symmetrical load on their legs. In the introductory session, dynamic exercises for small- and medium-sized muscle groups and lower extremity joints will be performed.…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of the computerized balance rehabilitation after hip fracture surgery

Kim¹,

Lee

Jung

et al. 2018

Medicine

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Introduction:Although balance problems in older populations are directly correlated with hip fractures, the overall physical gain afforded by balance rehabilitation itself has not yet been fully investigated. Here we describe a protocol for an open-label clinical trial to evaluate the effectiveness of computer-based balance-specific exercise (BSE) on the performance and balance of elderly women who underwent hip fracture surgery (HFS).Methods and analysis:Elderly female patients (≥65 years old) who underwent surgery for femoral neck, intertrochanteric, or subtrochanteric fracture regardless of surgery type will be included. The BSE will be conducted using a computed posturographic system for a 2-week intervention period following HFS. The primary outcome of this study is Berg balance scale score. All functional outcomes will be measured at 1 and 3 weeks and at 3 and 6 months after the surgical intervention. The data will be analyzed using the intention-to-treat principle.

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Effect of twelve-month physical exercise program on patients with osteoporotic vertebral fractures: a randomized, controlled trial

Abstract: This is the first 12 month-randomized clinical trial of exercise in osteoporotic women with a vertebral fracture that demonstrates improvement of three key outcome measures: quality of life, functional mobility, and balance.

Cited by 44 publications

References 26 publications

The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report

The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report

The Association between Nutrition and the Functional Outcomes of Elderly Women with Acute Vertebral Compression Fractures

Effectiveness of the computerized balance rehabilitation after hip fracture surgery

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