Effect of Twinlight Laser on the Attachment of Human Gingival Fibroblasts to the Root Surface In Vitro

Song, Jianing; Zheng, Han; Wu, Mingxuan; Guo, Xiaoman; Liu, Taohong

doi:10.12659/msm.932191

Cited by 2 publications

(2 citation statements)

References 30 publications

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“…This results in violent pressure perturbations throughout the fluid-filled volume, which can lead to secondary cavitation when the negative pressure threshold is exceeded [11] . In addition to the cavitation-induced biofilm removal, the laser energy can be used also for direct ablation-based surgical removal of biofilm and calculus [12] , [13] , [14] , [15] , [16] , [17] . However, direct ablation in difficult-to-reach spaces, especially in the periapical region, is hard to perform due to the inaccessibility of the area [18] , since the target area must be directly illuminated by the laser light.…”

Section: Introductionmentioning

confidence: 99%

Biofilm removal from Difficult-to-Reach places via secondary cavitation within a constrained geometry mimicking a Periodontal/Peri-Implant pocket

Volk,

Molan,

Šavli

et al. 2024

Ultrasonics Sonochemistry

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Section: Introductionmentioning

confidence: 99%

Biofilm removal from Difficult-to-Reach places via secondary cavitation within a constrained geometry mimicking a Periodontal/Peri-Implant pocket

Volk,

Molan,

Šavli

et al. 2024

Ultrasonics Sonochemistry

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“…Following an understanding of the indispensable role of fibroblasts in periodontal healing, extensive scientific inquiry has been undertaken to investigate diverse mechanical [12,13] and chemical root surface modifications [14][15][16][17]. The primary objective of these investigations was to reinstate the compromised root surface structure caused by the deleterious effects of periodontitis to a state conducive to encouraging fibroblast adhesion.…”

Section: Introductionmentioning

confidence: 99%

Fibroblast Viability Through Mechanical and Chemical Root Surface Modifications in Periodontal Healing: An In Vitro Comparative Study

Felemban

2023

Cureus

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Background: The wound-healing process incorporates a spectrum of periodontal therapeutic interventions that strive to restore the health and function of the periodontium. Fibroblasts play pivotal roles in tissue repair and regeneration. Extensive research has been focused on mechanical and chemical root surface modifications to enhance fibroblast adhesion, which is crucial for successful wound healing. Purpose: This study aimed to assess the combined efficacy of mechanical and chemical root surface modifications in promoting fibroblast viability to root surfaces affected by periodontitis in comparison to chemical modifications alone. Materials and methods: Root samples were collected from healthy individuals and those with advanced periodontitis. The specimens were prepared, and the experimental groups were categorized based on the type of surface modification with mechanical and/or chemical materials, including hyaluronic acid (HA), ethylenediaminetetraacetic acid (EDTA), enamel matrix derivatives (EMD), and EDTA/EMD. Fibroblasts were seeded onto previously treated root samples. Cell adhesion was assessed using a viability assay. Results: Fibroblast viability was significantly higher on root surfaces treated with chemical agents than on those treated with mechanical and chemical modifications. Long-duration EDTA and short-duration EMD treatments were significantly effective in enhancing cell viability. EDTA/EMD surface treatments resulted in significantly higher cell viability in all groups compared to the periodontitis root surfaces. Conclusion: EDTA, EMD, and their combined application can potentially ameliorate periodontitis-induced surface structural impairments. Mechanical surface debridement can significantly affect the effectiveness of EDTA and EMD root conditioning agents.

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Effect of Twinlight Laser on the Attachment of Human Gingival Fibroblasts to the Root Surface In Vitro

Cited by 2 publications

References 30 publications

Biofilm removal from Difficult-to-Reach places via secondary cavitation within a constrained geometry mimicking a Periodontal/Peri-Implant pocket

Biofilm removal from Difficult-to-Reach places via secondary cavitation within a constrained geometry mimicking a Periodontal/Peri-Implant pocket

Fibroblast Viability Through Mechanical and Chemical Root Surface Modifications in Periodontal Healing: An In Vitro Comparative Study

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