Effect of Ultrasonic Phacoemulsification on the Quality of Life of Patients with Nuclear-Cortical Cataract

Agarkov, N. M.; Yablokov, M.M.; Konyaev, D.A.; Попова, Е. В.

doi:10.18008/1816-5095-2021-2-325-330

Oftalʹmologiâ

2021

DOI: 10.18008/1816-5095-2021-2-325-330

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Effect of Ultrasonic Phacoemulsification on the Quality of Life of Patients with Nuclear-Cortical Cataract

N. M. Agarkov

M.M. Yablokov

D.A. Konyaev

et al.

Abstract: Currently, there are negative trends in the incidence of cataract, which, along with glaucoma, is the most common cause of visual impairment in various countries. Cataract prevalence continues to be high, necessitating the search for new treatment technologies and criteria for assessing the health and quality of life of this population. The purpose: to study the quality of life of patients with cataract against the background of ultrasonic phacoemulsification with implantation of soft intraocular lenses. Nei-V… Show more

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Cited by 2 publications

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Association of systemic cellullar immunity with the development of cataract

Osmanov

Фабрикантов

2022

Med. immunol.

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Among the causes of visual impairment, cataract occupies a significant proportion, which indicates a need for studying the causes of its development. Over recent years, an important role has been given to impaired immunoregulatory reactions in its genesis. So far, however, participation of systemic cellular immunity in occurence of different clinical types of cataract remains poorly known. The aim of the present study was to assess association between parameters of systemic cellular immunity and development of mature nuclear cataract. On the basis of IRTC “S.N. Fedorov Eye Microsurgery Center” (Tambov Branch), a study of major immune cells subpopulations in peripheral blood was performed over 2019-2020 in 63 patients aged 60-84 years, suffering from mature nuclear cataract (the study group). The control group consisted of 47 patients aged 60 to 84 years without ocular disorders in the history and at the time of examination. The evaluation of differentiated cell clusters was carried out with BD FACS Canto II flow cytometer. As a result, a statistically significant decrease in the absolute number of CD19+ to 0.18±0.003 × 109 /L was revealed in the patients from the main group versus 0.42±0.05 × 109 /L in controls; the relative number of CD19+ was decreased to 8.36±1.1% versus 19.64±1.3%, respectively, along with absolute content of CD3+ cells of 0.92±0.08 × 109 /L versus 1.57±0.06 × 109 /L in controls. On the contrary, the absolute number of CD56+ in the patients with mature nuclear cataract was significantly increased to 0.27±0.02×109 /L compared to 0.15±0.03 × 109 /L in the age control group. The relative risk values are statistically significant, and the highest levels were found for CD19+ and CD3+ cell clusters, which were 3.237 and 2.954 for the absolute number, and 1.952 and 2.748, for the relative number, respectively. These findings suggest that development of a mature nuclear cataract is associated primarily with a decrease in absolute and relative contents of B and T lymphocytes at the systemic level, which may be of practical importance when used as immunological markers of nuclear cataract.

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Association of systemic cellullar immunity with the development of cataract

Osmanov

Фабрикантов

2022

Med. immunol.

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Influence of the quality of viscoelastic removal on phacoemulsification results. Part 1. Type of the postoperative period course depending on the quality of viscoelastic removal in phacoemulsification

Егорова

Vasiliev

Bai

2021

Ophthalmology Reports

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BACKGROUND: The reasons for the development of postoperative reactive inflammation under optimal conditions for the operation are errors in the surgical technique and the presence of viscoelastic residues. The likelihood of developing ophthalmic hypertension exists with the use of viscoelastic of any type. Its incomplete evacuation can be explained by the difficult visualization due to its transparency. Analysis of the dependence of the postoperative period course on the quality of viscoelastic removal at phacoemulsification can be considered to be relevant and expedient. AIM: The aim was to study the type of the postoperative period course depending on the quality of viscoelastics removal at phacoemulsification. MATERIALS AND METHODS: 104 eyes of randomly chosen patients who underwent femto-laser assisted phacoemulsification, divided into 2 groups according to ophthalmic viscoelastics characteristics (colored or transparent). Both groups were split into 2 subgroups each depending on method of viscoelastics removal. Tonometry and biomicroscopy were performed 3 hours after phacoemulsification and on the post-op Day 1. Patients with Tyndall effect were examined daily until its disappearance. RESULTS: At comparable preoperative IOP indices, its elevation 3 hours after surgery took place in subgroups 2a and 2b, the highest being in subgroup 2a. The greatest number of eyes with Tyndall effect, at all follow-up periods, was found in subgroup 2a, the lowest in subgroup 1b. The total number of eyes with keratopathy (as epitheliopathy) observed 3 hours after surgery was 7, four of them being from subgroup 2a. CONCLUSIONS: The conducted research showed that the type of early postoperative period course of phacoemulsification depends on visualization possibility of the viscoelastic and of the method of its removal. Minimal changes of hydrodynamics and maximal number of eyes with absence of inflammation took place when using colored viscoelastic and impulse irrigation method.

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Effect of Ultrasonic Phacoemulsification on the Quality of Life of Patients with Nuclear-Cortical Cataract

Cited by 2 publications

References 10 publications

Association of systemic cellullar immunity with the development of cataract

Association of systemic cellullar immunity with the development of cataract

Influence of the quality of viscoelastic removal on phacoemulsification results. Part 1. Type of the postoperative period course depending on the quality of viscoelastic removal in phacoemulsification

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