Effect of urinary pH and flow rate on catecholamine excretion.

Aslan, Salih; Nelson, Lindsay M.; Carruthers, Malcolm; Lader, Malcolm

doi:10.1111/j.1365-2125.1979.tb00938.x

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…Meanwhile the 12 calculated correlation coefficients were ranging between r = 0.02 (NS) and r = 0.58 (p < 0.01) and only four of the calculated r were significant. This lack of a persistent positive correlation agrees with the data of several authors [4,9,18,62] who did not observe any significant relationship between diuresis and adrenaline or noradrenaline excreted in urine. Thus increases in these urinary cate cholamine seem unlikely to result from a wash-out phenomenon.…”

Section: Correlations Between Variablessupporting

confidence: 80%

The Effects of Psychosocial Stress on Urinary, Excretion of Adrenaline and Noradrenaline in 51- to 55- and, 71- to 74-Year-Old Men

et al. 1981

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The experiments were done to investigate modifications with aging in reactivity and speed of recovery of the sympathetic adrenomedullary system during psychosocial stress. Normal male volunteers were studied. Urinary adrenaline and noradrenaline, diuresis, pH and specific gravity were measured. Adrenaline and noradrenaline baseline levels were lower in the older age group. Adrenaline levels increased by the same percent during stress in the two age groups, but came back to pre-stress values more slowly in older subjects, as did blood pressure.

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Section: Correlations Between Variablessupporting

confidence: 80%

The Effects of Psychosocial Stress on Urinary, Excretion of Adrenaline and Noradrenaline in 51- to 55- and, 71- to 74-Year-Old Men

et al. 1981

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Consistency in catecholamine and cortisol excretion patterns over experimental conditions

Lundberg¹,

Forsman²

1980

Pharmacology Biochemistry and Behavior

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Effects of salt intake and renal denervation on catecholamine catabolism and excretion

Baínes¹

1982

Kidney International

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My study was designed to measure the effect of salt intake on secretion and catabolism of catecholamines by the kidney and renal nerve contributions to urinary catecholamine excretion. Rats with one chronically denervated (DEN) and one innervated (INN) kidney were fed either high salt (HS) or low salt (LS) diets for 5 to 14 days. Under Inactin anesthesia rats were expanded with isotonic saline while LS rats received 10% mannitol to produce the same urine flow rates. Epinephrine excretion was ten times greater from LS than from HS rats; however, epinephrine/inulin excretion was the same from INN and DEN kidneys. Norepinephrine/inulin excretion was 30% less from DEN than from INN kidneys in both HS and LS rats (P less than 0.01). Dopamine/inulin excretion was 20% less from the DEN kidney than from the INN kidney of HS rats (P less than 0.05), but the 5% lower dopamine/inulin excretion from DEN than from INN of LS rats was not significant. Norepinephrine and dopamine tubular secretions from the rats, estimated by microinjecting radioactive tracers beneath the renal capsule, were 21 and 65%, respectively. After the microinjection, 68% of radioactive norepinephrine and 65% of radioactive dopamine were secreted unchanged. Catecholamine secretion rates and catabolism were not altered by denervation or different salt intakes. Estimated neural NE release was 1 ng/min in INN kidneys of both HS and LS rats; dopamine release 0.6 ng/min in kidneys of HS rats. Thus, when anesthesized, renal nerves contribute 30% to urinary NE and up to 21% to urinary dopamine excretion. Salt intake did not influence NE release from renal nerves or catecholamine secretion and catabolism by the kidney, but salt depletion decreased the renal nerve contribution to urinary dopamine excretion.

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Effect of urinary pH and flow rate on catecholamine excretion.

Cited by 4 publications

References 11 publications

The Effects of Psychosocial Stress on Urinary, Excretion of Adrenaline and Noradrenaline in 51- to 55- and, 71- to 74-Year-Old Men

The Effects of Psychosocial Stress on Urinary, Excretion of Adrenaline and Noradrenaline in 51- to 55- and, 71- to 74-Year-Old Men

Consistency in catecholamine and cortisol excretion patterns over experimental conditions

Effects of salt intake and renal denervation on catecholamine catabolism and excretion

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