“…He et al [22] showed in their study that astaxanthin prevents ovarian aging by improving the antioxidant capacity in the body of laying hens and enhancing the level of production of reproductive hormones, Gao et al [59] who found when adding astaxanthin at a level of 25, 50 and 100 mg/kg feed to the diet of laying hens at the age of 50 weeks led to an improvement in the level of total antioxidant capacity and glutathione peroxidase enzyme in blood plasma and a significant decrease (P<0.05) in blood plasma, the level of malondialdehyde (MDA) compared with the control treatment, and the improvement in these traits increased linearly with increasing the level of astaxanthin to the diet, also the results agreed with Heng et al [49] when adding astaxanthin at levels of 0, 20, 40, 80 and 160 mg/kg feed to the diet of laying hens a significant increase (P<0.05) was found for the coefficients of adding astaxanthin in the level of glutathione peroxidase and a significant decrease (P<0.05) in the level of malondialdehyde in the blood plasma compared with the control treatment, The results also agreed with the findings of Dansou et al [60], as they showed that when adding astaxanthin at levels of 0, 7.1, 14.2, 21.3, and 42.6 mg / kg feed to the laying hens diet, the activity of antioxidant enzymes increased and the level of malondialdehyde (MDA) decreased. They explained the reason this is due to the fact that antioxidants work to modify the enzymatic system in the ovaries by increasing the levels of antioxidant enzymes and reducing programmed cell death in the ovaries by regulating the enzymatic system in the ovaries, also the results agreed with Zhu et al [56] when adding astaxanthin to the diet of laying hens it led to a significant increase (P<0.05) in the level of glutathione peroxidase and catalase in blood plasma, and a significant decrease (P<0.05) in the level of malondialdehyde (MDA) compared with the control treatment.…”