Effect of Verapamil Adjuvant with Local Anaesthetic Mixtures in Supraclavicular Brachial Plexus Block

Ali, Arman; Rahman, Lutfur; Hassan, Mehdi; Rahman, Rezwanur; Asfia, Kai Nur; Rahman, Mohammad Anisur; Ahmed, Sharmeen

doi:10.3329/bmj.v46i2.40218

Cited by 3 publications

(4 citation statements)

References 10 publications

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“…Dr. Md. Arman Ali, et al [12] found similar results in a similar study and concluded that verapamil can be used as an adjuvant to decrease the onset time of sensory and motor blocks of bupivacaine in supraclavicular block. Sidharth sraban routray, et al [11] in their study also concluded that Verapamil, when added to Levobupivacaine in supraclavicular brachial plexus, increased the duration of sensory and motor block.…”

Section: Discussionmentioning

confidence: 63%

Effect of verapamil as an adjuvant to Levobupivacaine in supraclavicular brachial plexus block

Atram¹,

Mundrawala²

2021

Int. J. Med. Anesthesiology

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Background: The quest for searching newer and safer anaesthetic agents has always been one of the primary needs in anaesthesiology practice. Levobupivacaine, the pure s (-) enantiomer of bupivacaine, has strongly emerged as a safer alternative for regional anaesthesia than its racemic sibling. Also, many adjuvants have been used with local anaesthetics to reduce the time of onset and prolong the duration of analgesia in brachial plexus blocks. However, few studies are there using verapamil as an adjuvant with Levobupivacaine. Aims: The primary aim of the study is to know the effect of verapamil (5mg) as an adjuvant to Levobupivacaine in supraclavicular brachial plexus block. Methods: A Descriptive, Observational study was carried out in 80 ASA Grade I and II patients, undergoing upper limb surgeries under supraclavicular brachial plexus block using ultrasound machine. Local anaesthetic solution was prepared as following. 30ml 0.5% Levobupivacaine + 2ml Verapamil (5mg). The effect of Verapamil as an adjuvant to Levobupivacaine in Supraclavicular Brachial Plexus Block with regards to onset and duration of motor and sensory block, duration of analgesia, need for rescue analgesia and number of rescue analgesia in first 24 hours after surgery was evaluated. Data analysis was done with the help of SPSS Software ver 13. Results: Mean onset time for motor block in our study group was 9.19 ± 1.86min The mean duration of motor block in our study group was 470.25 ± 42.00 min The mean onset time for sensory block in our study group was 6.48 ± 2.55 min The mean duration of sensory block in our study group was 494.88 ± 37.67 min The mean duration of analgesia in our study group was 517. 88 ± 48.24 The mean no of reuse analgesia required in the first 24 hours after surgery was 3 Conclusion: Verapamil (5 mg) 2 ml can be effectively and safely used as an adjuvant to Levobupivacaine (0.5%) 30ml in Supraclavicular Brachial Plexus Block. However, due to paucity of studies in literature, there is still scope for further study using different calcium channel blocking drugs or in different dosage strengths.

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Section: Discussionmentioning

confidence: 63%

Effect of verapamil as an adjuvant to Levobupivacaine in supraclavicular brachial plexus block

Atram¹,

Mundrawala²

2021

Int. J. Med. Anesthesiology

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“…In addition, a person who participates in voluntourism is driven by motivation. Several studies (Ali & Rahman, 2019;Han et al, 2019;Otoo & Amuquandoh, 2014;Proyrungroj, 2017) additionally propose that the inspiration of volunteer sightseers is multi-layered, and their inspiration incorporates both to and fro factors. In the meantime, persuasive variables are the hypothetical methodologies most broadly utilized to grasp traveler inspiration (John & Larke, 2016;Michael et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Voluntourism: Motivations of Gen Z Participants in Bali

Ni Putu Evi Wijayanti,

Ni Komang Anggy Septiani,

Putu Ayu Aryasih

et al. 2024

Pusaka: J. Tour. Hosp. Travel Bus. Event

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Voluntourism is becoming an increasingly popular phenomenon among Generation Z (Gen Z) in Indonesia. This study examines the motivations of Gen Z volunteer tourists who participate in voluntourism activities in Bali. This study used a qualitative descriptive approach. The informants used consisted of twenty-six Gen Z tourists in Indonesia, all selected through non-probability and snowball sampling. The result shows that Gen Z tourists are motivated by push and pull factors, including helping others, gaining new experiences, meeting new friends, personal development and growth, interest in culture, visiting Bali and personal interest in specific volunteering activities. This study provides an in-depth insight into how Gen Z views voluntourism not only as a means to explore exotic destinations such as Bali but also as an opportunity to make a positive contribution to the local community. The implications of these findings can provide valuable guidance for the tourism industry and volunteer organisations in order to develop more relevant and meaningful voluntourism programs for Gen Z

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“…Local anaesthetic agent provides analgesia not more than 4-8 hours [1] . Drugs belonging to calcium blockers, opioids, ketamine, adrenaline, alpha2 adrenergic agonist are used as adjuvants to increase analgesic ability and decrease the incidence of side effects [2] . Supraclavicular brachial plexus block is carried out at the division level, which had rapid onset and deep level of block.…”

Section: Introductionmentioning

confidence: 99%

“…Supraclavicular brachial plexus block is carried out at the division level, which had rapid onset and deep level of block. In recent time, supraclavicular block has gained extensive fame with addition of adjuncts to local anaesthetic solution to increase its efficacy and duration [2,3] . Verapamil is a drug of calcium channel blocker that is used as adjuvant to local anaesthetic agents in peripheral nerve block.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of analgesic properties of verapamil as an adjuvant with 0.25% bupivacaine in USG guided supraclavicular brachial plexus block

Mamidi¹,

Prasad²

2021

Int. J. Med. Anesthesiology

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Background: Peripheral nerve blocks are extensively preferred in perioperative pain management. Adding calcium blockers to local anesthetics agents can prolong the duration of analgesia. Verapamil, a calcium channel blocker is used extensively as an adjunct to lignocaine or bupivacaine for brachial plexus block due to its prolonged duration of action. This study was designed to evaluate whether additional anaesthetic and analgesic effect could be derived from administration of verapamil to 0.25% bupivacaine in supraclavicular brachial plexus block. Material and Methods: A total of 76 cases underdoing upper limb surgeries between age group 21 to 65 years belong to ASA grade I and II were recruited. Cases were randomly divided into 2 groups i.e. group 1 with USG guided brachial plexus block using 30ml of 0.25% bupivacaine with 2ml of normal saline and group 2 with 30 ml of 0.25% bupivacaine with 5mg of verapamil diluted to 2ml. Parameters like pulse rate, blood pressure, Spo2 were recorded before and after the block. Results: The mean difference of onset and duration of sensory and motor blockade between two study groups was statistically significant (P<0.005). The mean difference of duration of rescue analgesia was statistically significant between two study groups (P<0.003). The mean pulse rate, systolic blood pressure, diastolic blood pressure and oxygen saturation levels was comparable between two study groups and mean difference was statistically not significant (p>0.005). Conclusion:Verapamil as an adjunct to 0.25% bupivacaine in supraclavicular brachial plexus block acts efficiently in maintaining prolonged duration of analgesia.

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Effect of Verapamil Adjuvant with Local Anaesthetic Mixtures in Supraclavicular Brachial Plexus Block

Cited by 3 publications

References 10 publications

Effect of verapamil as an adjuvant to Levobupivacaine in supraclavicular brachial plexus block

Effect of verapamil as an adjuvant to Levobupivacaine in supraclavicular brachial plexus block

Voluntourism: Motivations of Gen Z Participants in Bali

Evaluation of analgesic properties of verapamil as an adjuvant with 0.25% bupivacaine in USG guided supraclavicular brachial plexus block

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