Effect of Vitamin D Supplementation on Postoperative Outcomes in Cardiac Surgery Patients: A Systematic Review

Abstract

Background Vitamin D deficiency is a very common occurrence in cardiac patients. It has been proved that cardiac surgery and cardiopulmonary bypass accelerate the deficiency further. The postoperative outcomes of patients deteriorate in the presence of vitamin D deficiency. Perioperative supplementation of vitamin D is the only solution to the problem. Hence, the present systematic review was conducted to derive the efficacy and safety of vitamin D supplementation on postoperative outcomes in cardiac surgery patients. Method Publications over duration of last 10 years was searched from different database and web sites. The data from full-text research articles were analyzed for the effect on different postoperative outcomes and side effects. Result Eight randomized control trials were retrieved on the effect of perioperative vitamin D supplementation in cardiac surgery patients and their postoperative outcomes. Six articles (75%) were found to be in favor of improvement in postoperative outcome. Two articles (25%) did not find any difference of outcome between the control and treatment group. All the studies observed the restoration of vitamin D to normal and no adverse effects from supplementation. Conclusion Perioperative vitamin D supplementation improves the postoperative outcomes after cardiac surgery. It is effective and safe to supplement vitamin D in cardiac surgery patients.

The Possible Influence of Vitamin D Levels on the Development of Atrial Fibrillation—An Update

“…Using the conclusions of meta-analyses devoted to this topic, the above uncertainties can be partially answered. Of the seven meta-analyses that focused on the level of VitD and its relationship to PoAF frequency, six indicated a significant effect of the VitD concentration [ 43 , 101 , 102 , 103 , 104 , 105 , 106 ]. One contrary paper also clustered papers on IAF and did not distinguish between them, so we decided to treat the aforementioned four as prognostic [ 43 ].…”

A New Journey Begins

“…Most importantly, the journal is indebted to its authors who over the years have published excellent articles in the journal covering various engaging topics such as randomized trials exploring use of probiotics in prevention of ventilator associated pneumonia, [1] or comparing complex observations of anesthetic agents and barbiturate in Patients Undergoing Elective Coronary Artery Bypass Surgery, [2] to the risk of acute kidney injury development in patients with acute decompensated heart failure [3] etc. Time to time the journal keeps bringing for its authors, engaging, and educative narrative as well as systematic reviews discussing topics such as, effect of Vitamin D supplementation on post-operative outcomes in cardiac surgery patients, [4] hypercoagulation in infectious diseases, [5] and the significance of nutrition support following cardiac surgery. [6] Continuing to serve the moto to bring educative and information content for its readers and aid researches to reach out to a global audience, the journal in its 7 th Vol.…”