Effect of warming anesthetic solutions in injection pain during dental anesthesia. A Randomized clinical trial.

Aravena, Pedro; Barrientos, Camila; Troncoso, Catalina

doi:10.17126/joralres.2015.060

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…The sample size was based on a pilot study 15 who showed a mean difference of 18.5 points on the visual analog scale (VAS) using local anesthetic at 42°C. Considering a 5% level of significance, a study power of 90% and including 25% of the sample in case of loss of observers, a total of 70 subjects were estimated.…”

Section: Methodsmentioning

confidence: 99%

Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial

Aravena

Barrientos

Troncoso

et al. 2018

LRA

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BackgroundThe purpose of this study is to determine the effectiveness of warming anesthesia on the control of the pain produced during the administration of dental anesthesia injection and to analyze the role of Transient Receptor Potential Vanilloid-1 nociceptor channels in this effect.Patients and methodsA double-blind, split-mouth randomized clinical trial was designed. Seventy-two volunteer students (22.1±2.45 years old; 51 men) from the School of Dentistry at the Universidad Austral de Chile (Valdivia, Chile) participated. They were each administered 0.9 mL of lidocaine HCl 2% with epinephrine 1:100,000 (Alphacaine®) using two injections in the buccal vestibule at the level of the upper lateral incisor teeth. Anesthesia was administered in a hemiarch at 42°C (107.6°F) and after 1 week, anesthesia was administered by randomized sequence on the contralateral side at room temperature (21°C–69.8°F) at a standardized speed. The intensity of pain perceived during the injection was compared using a 100 mm visual analog scale (VAS; Wilcoxon test p<0.05).ResultsThe use of anesthesia at room temperature produced an average VAS for pain of 35.3±16.71 mm and anesthesia at 42°C produced VAS for pain of 15±14.67 mm (p<0.001).ConclusionThe use of anesthesia at 42°C significantly reduced the pain during the injection of anesthesia compared to its use at room temperature during maxillary injections. The physiological mechanism of the temperature on pain reduction could be due to a synergic action on the permeabilization of the Transient Receptor Potential Vanilloid-1 channels, allowing the passage of anesthetic inside the nociceptors.

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Section: Methodsmentioning

confidence: 99%

Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial

Aravena

Barrientos

Troncoso

et al. 2018

LRA

Self Cite

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“…Operator-defined techniques such as troncular injections, injection administration speeds below 1 tube per minute, and the compression of the tissue surrounding the puncture site have also been used. 8 Warming the local anesthetic solution to body temperature 9 has been found to effectively reduce pain during injection for eye surgery 10 and plastic surgery and thus may have relevance in dentistry. 11 Another technique that has been used in the past, but is fast regaining popularity in recent years, is to add a buffer to raise the pH of the anesthetic solution.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of anesthetic efficacy of warm, buffered and conventional 2% lignocaine for the success of inferior alveolar nerve block (IANB) in mandibular primary molars: A randomized controlled clinical trial

Kurien

Goswami

Singh³

2018

J Dent Res Dent Clin Dent Prospects

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Background: Maintaining primary teeth in the oral cavity is of prime importance, and grossly carious teeth may require pulp therapy for the same. Pain on injection and incomplete anesthesia causes failure of the procedure and result in fear and anxiety. Various methods have evolved to overcome this; such as distraction, topical anesthesia, etc. A few techniques regaining popularity in dentistry in recent times is the warming or buffering of the solution prior to administration. This study thus aimed to compare and evaluate the anesthetic efficacy and the patient’s pain reaction to pre-warmed, buffered and conventional 2% lignocaine for the success of Inferior Alveolar Nerve Block in mandibular primary molars undergoing pulp therapy. Methods: The study is a randomized, split-mouth trial. Sixty children between six -12 years, requiring pulp therapy bilaterally on mandibular primary molars, were administered conventional, buffered or pre-warmed 2% lignocaine on two separate appointments. Various parameters were assessed using objective and subjective scales. Results: Pre-warmed and buffered anesthetics had lesser pain on injection (p<0.001, p<0.001) and pulp therapy (p=0.001, p=0.014), faster onset of action (p=0.004, p=0.001), lower SEM Sound (p=0.035, p=0.028), Eye (p< 0.001, p=0.013) and Motor (p=0.008, p=0.021) scores and shorter duration of action (p< 0.001, p=0.015). No significant difference was found between the two modified solutions. Thus pre-warmed and buffered anesthetic solutions fared better than the conventional solution for all parameters but had no advantage over each other. Conclusion: Buffering or pre-warming the anesthetic solution reduces pain on administration and during procedures in children. Trial registration number: CTRI/2017/02/007922

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Local Anesthesia in Dentistry

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Effect of warming anesthetic solutions in injection pain during dental anesthesia. A Randomized clinical trial.

Cited by 3 publications

References 14 publications

Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial

Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial

Comparative evaluation of anesthetic efficacy of warm, buffered and conventional 2% lignocaine for the success of inferior alveolar nerve block (IANB) in mandibular primary molars: A randomized controlled clinical trial

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