Effect of warming bupivacaine 0.5% on ultrasound-guided axillary plexus block. Randomized prospective double-blind study

Trabelsi, W.; Gabsia, A. Ben; Lebbi, A.; Sammoud, W.; Labbène, Iheb; Kchelfi, S.; Ferjani, Mustapha

doi:10.1016/j.otsr.2016.10.010

Cited by 6 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study has revealed that the administration of 0.5% ropivacaine at a temperature of 30℃ can signi cantly speed up the onset time for both sensory and motor block in subgluteal sciatic nerve, which is consistent with previous researches on brachial plexus block [22][23][24]. Compared to brachial plexus blocks, warming local anesthetics for the subgluteal sciatic nerve holds greater clinical signi cance due to its thicker construction and slower onset time.…”

Section: Discussionsupporting

confidence: 90%

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

He,

Ma,

Zhou

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Currently, no information is available on the influence of local anaesthetics at different temperatures on sciatic nerve block. This study aims to determine whether warming ropivacaine has an influence on the onset of subgluteal sciatic nerve block under the ultrasonic guidance . Methods Fifty-four patients with distal lower limbs surgery were randomly allocated into warming group (group W, n = 27 ) or room tempeture gruop (group R, n = 27 ). A sciatic nerve block with subgluteal approach under ultrasound guidance was performed with either 30 ml of 0.5% ropivacaine at a temperature of 23℃for group R or 30 ml of 0.5% ropivacaine at a temperature of 30℃for group W. The sensory and motor blockade were assessed every 2 minutes over a 30-minute period following injection.The primary outcome was the onset of limb sensory block . Results In comparison with the group R, the time to onset of motor and sensory block in group W was significantly reduced. No obvious differences for the satisfaction of patients and duration of anesthesia were discovered between both groups. No complications associated with nerve block were observed 2 days after surgery. Conclusions Warming ropivacaine 0.5% to 30℃ received a significantly faster onset of anesthesia during subgluteal sciatic nerve block. Trial registration The trial was registered on October 3, 2022 in the Chinese Clinical Trial Registry (https://www.chictr.org.cn/bin/project/edit?pid=181104), registration number ChiCTR2200064350.(03/10/2022).

show abstract

Section: Discussionsupporting

confidence: 90%

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

He,

Ma,

Zhou

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…7, 13 According to Trabelsi et al, heating increases the diffusion capacity of local anaesthetic, thereby resulting in early onset of the action. 14 The duration of sensory blockade and the median highest sensory level has shown comparable results without any significance. Twosegment regression and the motor characteristics of the subarachnoid block were comparable among both groups.…”

Section: Figure 4 -Number Of Patients With Hypotension Episodes In Ea...mentioning

confidence: 91%

Comparison of Subarachnoid Block Characteristics with Levobupivacaine at 24<sup>0</sup>C and 37<sup>0</sup>C for Infra-Umbilical Surgeries - a Randomized Controlled Trial

Nag¹,

Charles

Balachandar

et al. 2022

Sri Lankan J Anaesthesiol

View full text Add to dashboard Cite

Background & Aim: The temperature of a local anaesthetic solution influences its pKa and molecular kinetic activity, thereby affecting baricity. We evaluated the effects of 0.5% Levobupivacaine preheated at 37ºC on sensory and motor block characteristics and haemodynamic in patients undergoing infra-umbilical surgeries. Methods: This was a prospective, randomised, double blinded study, in which 70 patients were allocated into two groups [Group A (n=35) and Group B (n=35)]. In Group A, patients were administered 3 mL of levobupivacaine 0.5% solution at room temperature (24 -28ºC) and patients in Group B were administered with 3 mL of levobupivacaine 0.5% solution at 37°C (Thermostatically controlled digitalized hot bath machine) into the subarachnoid space. Our primary objective was to determine the time of onset of sensory blockade at T10. Time of onset and duration of motor blockade, duration of analgesia, time to two segment regression and other adverse events after spinal anaesthesia were secondary objectives. Results:The time to reach a sensory block of T10 was significantly shorter in group B (Mean ±SD 2.7±2.9 min, P 0.005) compared to that in group A (Mean ±SD 4.8±4.5 min). The mean duration of sensory block was longer in group B (Mean ±SD 155.5±25.9 min, P 0.048). Time to onset of motor block, duration of motor block and time to regression of two dermatomal level were not found statistically significant among the two groups. Conclusion: Spinal anaesthesia with 0.5% levobupivacaine heated to 37ºC shortens sensory block onset time and provides longer block duration.

show abstract

“…In the literature, few studies focused on the effect of warming local anesthetics on peripheral nerve block [ 6 ]. To our knowledge, they were only limited to brachial plexus block.…”

Section: Introductionmentioning

confidence: 99%

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

He,

Ma,

Zhou

et al. 2023

BMC Anesthesiol

View full text Add to dashboard Cite

Background There is a long latent period for the sciatic nerve block before a satisfactory block is attained. Changes in the temperature of local anesthetics may influence the characters of the peripheral nerve block. This study was designed to evaluate the effect of warming ropivacaine on the ultrasound-guided subgluteal sciatic nerve block. Methods Fifty-four patients for distal lower limbs surgery were randomly allocated into warming group (group W, n = 27) or room tempeture group (group R, n = 27) with the ultrasound-guided subgluteal sciatic nerve block. The group W received 30 ml of ropivacaine 0.5% at 30℃ and the group R received 30 ml of ropivacaine 0.5% at 23℃. The sensory and motor blockade were assessed every 2 min for 30 min after injection. The primary outcome was the onset time of limb sensory blockade. Results The onset time of sensory blockade was shorter in group W than in group R (16 (16,18) min vs 22 (20,23) min, p < 0.001), and the onset time of motor blockade was also shorter in group W than in group R (22 (20,24) min vs 26 (24,28) min, p < 0.001). The onset time of sensory blockade for each nerve was shorter in group W than in group R (p < 0.001). No obvious differences for the duration of sensory and motor blockade and the patient satisfaction were discovered between both groups. No complications associated with nerve block were observed 2 days after surgery. Conclusions Warming ropivacaine 0.5% to 30℃ accelerates the onset time of sensory and motor blockade in the ultrasound-guided subgluteal sciatic nerve block and it has no influence on the duration of sensory and motor blockade. Trial registration The trial was registered on October 3, 2022 in the Chinese Clinical Trial Registry (https://www.chictr.org.cn/bin/project/edit?pid=181104), registration number ChiCTR2200064350 (03/10/2022).

show abstract

Effect of warming bupivacaine 0.5% on ultrasound-guided axillary plexus block. Randomized prospective double-blind study

Abstract: Warming bupivacaine 0.5% to 37°C accelerated onset of sensory and motor block and extended action duration.

Cited by 6 publications

References 15 publications

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

Comparison of Subarachnoid Block Characteristics with Levobupivacaine at 24<sup>0</sup>C and 37<sup>0</sup>C for Infra-Umbilical Surgeries - a Randomized Controlled Trial

The effect of warming ropivacaine on ultrasound-guided subgluteal sciatic nerve block: a randomized controlled trial

Contact Info

Product

Resources

About