Effect of α-mangostin from Garcinia mangostana on Osteoblast cells in the Wound Healing Process: A Review

Abstract

Preservation of the socket after a tooth extraction is necessary to maintain the dimensions of the alveolar bone. In addition, it can speed up the healing process while preventing bone resorption. Previous research has shown that α-mangostin contained in mangosteen (Garcinia mangostana) rind can reduce alveolar bone resorption, while accelerating the bone healing process. The purpose of this study is to describe the relationship between the inflammatory process and osteoblastic differentiation after administration of α-mangostinto osteoblast cells.The inflammatory process decreased and osteoblast differentiation increased after the application of alpha-mangostin to osteoblast cells.