Effect of β-Carotene and Canthaxanthin ontert-Butyl Hydroperoxide-Induced Lipid Peroxidation in Murine Normal and Tumor Thymocytes

Effects of LDL‐immunoapheresis on plasma concentrations of vitamin E and carotenoids in patients with familial hypercholesterolemia

“…Even though a-tocopherol, bcarotene, and retinol are partially removed by LDL apheresis, vitamin E deficiencies and impaired carotenoid status are rarely seen in patients treated with LDL apheresis, possibly also due to the fact that in many centers patients are routinely supplemented with vitamin E and occasionally perhaps also b-carotene [4,5]. Other carotenoids in plasma include canthaxanthin, which has been shown to be a more potent antioxidant than b-carotene [6], and lycopene, which has been described to be the most efficient biological oxygen quencher [7]. Little is known about LDL immunoapheresis and removal of c-tocopherol and the other carotenoids including a-carotene, lycopene, zeaxanthin, cryptoxanthin, and canthaxanthin.…”

Carotenoids in Avian Nutrition and Embryonic Development. 2. Antioxident Properties and Discrimination in Embryonic Tissues.

“…, normal and tumor thymocytes (Palozza et al, 1996), kidney fibroblasts (O'Connor and O'Brien, 1998), embryonic hippocampal cultures (Mitchell et al, 1999), embryo fibroblast (Zhang et al, 1991), ovary cells (Weitberg et al, 1985), primary cultures of chicken embryo fibroblasts (Lawlor and O'Brien, 1995;, leukemia HL-60 cells (Hiramoto et al, 1999), monocyte-macrophages (Carpenter et al, 1997;Levy et al, 1996), cultured Ito cells (Kim et al, 1997), LDL in different systems (Dugas et al ,1999;Jialal et al ,1991;Oshima et al,1996), Salmonella typhimurim (DeMejia et al, 1997), pigmented yeast Rhodotorula mucilaginosa (Moore et al, 1989) and liver microcosms (Nakagawa et al, 1997;Vile and Winterbourn (1988). assembly.…”

β-Carotene Production and Its Role in Sclerotial Differentiation of Sclerotium rolfsii

“…which can cause lipid peroxidation (Simic, 1992;Stratton and Liebler, 1997). These ROS can be generated from light-sensitive reactions and from lightinsensitive reactions (i.e., lipid peroxidation reactions) and other oxidative stress growth conditions (Burton and Ingold, 1984;Khopde et al, 1998;Palozza et al, 1996;Simic, 1992). Therefore, ROS can form in S. rolfsii in the dark also, although to a lesser degree, especially as the fungus uses up its nutrients.…”

“…Our theory predicts that antioxidants are expected to decrease sclerotial differentiation by lowering oxidative stress. Since ␤-carotene can be incorporated into eucaryotic cells in culture and can lower oxidative stress by its lipid antioxidant action (Cooney et al, 1993;Palozza et al, 2000Palozza et al, , 1997Palozza et al, , 1996, we studied its effect on lipid peroxidation and on sclerotial differentiation of S. rolfsii at high oxidative growth conditions using the following criteria (Halliwell, 1997;Halliwell and Gutteridge, 1986): its antioxidant effect (i) on degree of differentiation and (ii) on lipid peroxidation should be concentration-dependent at concentrations not affecting growth rate (i.e., G.T.) of S. rolfsii.…”

“…Extraction of carotenoids from S. rolfsii whole colonies (mycelia with sclerotia), mycelia, and sclerotia was carried out by a modification of a previously reported method (Palozza et al, 1996). SI, SD, and SM sclerotia were picked very gently from their stems with stainless steel forceps that had their tips covered with Teflon ribbon.…”