Both individual and environmental factors predict externalizing behaviors and substance use (EB-SU); however, different patterns of interaction among these factors may have different implications. This review first examines how temperament and the family environment interact in the prediction of adolescent EB-SU. Second, studies are reviewed according to two theoretical models: (1) diathesis-stress, i.e., certain individual characteristics are linked to vulnerability and later problems in adverse environments; (2) differential susceptibility, i.e., these characteristics are linked to susceptibility, predicting problems in adverse environments, but also better than average outcomes in good environments. Fourteen studies focusing on the prediction of EB-SU at ages 12-18 were selected through a literature search. Results showed that certain temperament traits (high levels of impulsivity and disinhibition; low levels of effortful control, negative affect, fearfulness and shyness), hereby designated as "adventurous" disposition, were associated with higher levels of EB-SU in adverse family environments. Some studies also showed that children with "adventurous" temperament traits in positive environments had the lowest levels of EB-SU. This suggests that prevention of EB-SU might target family factors such as parenting and focus on children with "adventurous" temperament traits. Further, studies that supported the differential susceptibility model were those assessing temperament and the family environment in childhood and studies that supported the diathesis-stress model assessed these variables in adolescence. It is thus possible that some of these "adventurous" temperament traits, with regard to EB-SU, would be indicators of susceptibility to both enriched and adverse environments in childhood but no
CIHR Author ManuscriptCIHR Author Manuscript CIHR Author Manuscript longer in adolescence, when they would only be indicators of vulnerability to adverse environments.
KeywordsDiathesis-stress; Differential susceptibility; Temperament; Family; Externalizing; Moderation Adolescent substance use has several adverse short-and long-term consequences, including addiction, poor academic achievement, sleep disturbances, depression, suicidal behavior, injuries, overdoses, car accidents, teenage pregnancy, sexually transmitted diseases and liver disease (Newbury-Birch et al., 2009;Single, Rehm, Robson, & Van Truong, 2000;Stolle, Sack, & Thomasius, 2009). Correlates of substance use in adolescence include both individual and environmental characteristics (Chartier, Hesselbrock, & Hesselbrock, 2010;Patrick & Schulenberg, 2013). While internalizing problems are more strongly associated with substance use in adulthood (Chan, Dennis, & Funk, 2008;Grant et al., 2004;King, Iacono, & McGue, 2004), a history of externalizing behaviors beginning in early childhood is more likely to be observed in adolescents using substances (Chan et al., 2008;Jester et al., 2008;Pingault et al., 2013;Zucker, Heitzeg, & Nigg, 2011). Furthermore,...