Effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Shinjoh, Masayoshi; Miyairi, Isao; Hoshino, Ken; Takahashi, Tsuyoshi; Nakayama, Tetsuo

doi:10.1016/j.vaccine.2008.09.076

Cited by 77 publications

(98 citation statements)

References 8 publications

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“…Immunizations using live-attenuated vaccines are often difficult to perform in children undergoing orthotopic liver transplantation (OLT) [3]. The window of opportunity for vaccination prior to OLT is usually limited because the disease course of these children is often unstable.…”

Section: Introductionmentioning

confidence: 99%

“…After OLT, the seroconversion rate can be lower, and theoretical risks of infection and rejection due to live vaccine viruses exist. There are few reports regarding immunization using live-attenuated vaccines after liver transplantation [3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

“…Written informed consent was collected. We included the study on 70 immunizations for 18 cases that we reported in 2008(Shinjoh et al, 2008. Results: A total of 196 immunizations were administered to 48 pediatric post-LDLT recipients.…”

mentioning

confidence: 99%

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Updated data on effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Shinjoh

Hoshino

Takahashi

et al. 2015

Vaccine

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Updated data on effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Shinjoh

Hoshino

Takahashi

et al. 2015

Vaccine

Self Cite

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“…7 PDE3 and PDE7 are also expressed in inflammatory cells, and PDE5 was initially used to treat patients with exercise-induced asthma and showed bronchodilator effects. 8,9 One major limitation of the current study is the fact that the initial discovery sample used for the GWAS is underpowered to detect loci with small effect size. We have attempted to address this issue by validating the PDE11A association in a larger set of cases and controls, albeit from the same study population, as well as compare our case allele frequencies to additional sets of publicly available control samples (see Table E4 in the Online…”

Section: To the Editormentioning

confidence: 99%

Methacholine is more sensitive than mannitol for evaluation of bronchial hyperresponsiveness in children with asthma

Andregnette-Roscigno

Fernández‐Nieto

Potro

et al. 2010

Journal of Allergy and Clinical Immunology

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“…Although previous studies shows that immunization with liveattenuated vaccines are contraindicated in post-transplant children, Shinjoh et al recommended that immunization using selected live-attenuated vaccines were safe and effective for post-transplant children who were not severely immunosuppressed (7). But other serologic studies shows that it is much more better to do so before transplantation rather than after that.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of immunity status to routine vaccination in pediatric liver transplant candidates

Dehghani

Shakiba

Ziaeyan³

et al. 2015

Turk J Gastroenterol

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Background/Aims: Generally, prevention of infections by vaccination is the least invasive and most cost-effective approach to reduce the incidence of infections and the morbidity and mortality in transplant recipients. Genetic diversity and different liver disease among patients contributes to variability in immune responses to vaccines and pathogens. The aim of this study was to evaluate immunity status to different vaccinated organisms in pediatric liver-transplant candidates. Materials and Methods: The vaccination charts of 90 patients who were referred to Organ Transplant Center of Shiraz University of Medical Sciences were reviewed and compare with National Immunization Program recommendation, after that 10 mL blood was drawn from these patients for serologic studies by ELISA. Results: Eighty percent of the patients had protective antibody titers for poliomyelitis, 65.6% for rubella, 62.3% for diphtheria, 60% for tetanus, 57.7% for pertussis, 55.5% for measles, 42.2% for hepatitis B and 36.7% for mumps. Conclusion: Overall seroconversion rates were not satisfactory for many infections that may be due to lower rate of vaccination or even the underlying liver disease that interfere with optimal immunogenecity of vaccination. Therefore, vaccination charts should be periodically reviewed and updated, also repeated measurements of serum antibodies and appropriate revaccination if titers decline is recommended to prevent the vaccine-preventable disease in liver transplant candidates after transplant.

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Effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Cited by 77 publications

References 8 publications

Updated data on effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Updated data on effective and safe immunizations with live-attenuated vaccines for children after living donor liver transplantation

Methacholine is more sensitive than mannitol for evaluation of bronchial hyperresponsiveness in children with asthma

Evaluation of immunity status to routine vaccination in pediatric liver transplant candidates

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