Leadership and management are necessary for all potential registered nurse (RN) leaders. Every nurse has some degree of management and leadership responsibility. The healthcare workforce, effective leadership, and decision-making are priority topics. Other topics include achieving clinical and operational excellence, which includes, but is not limited to, innovation, patient advocacy, quality, diversity, equity, and adapting to changes in hospital and interdepartmental policies and procedures. This is a pre- and post-study for leadership training aiming to equip all potential RN leaders with confidence and knowledge in leading the center for achieving sustainable success of the organization. Through interactive lectures and workshops, the objective of the study is to enhance knowledge regarding staff plan management, to develop administrative and management skills, to enhance knowledge regarding supply management and storage standards, to ensure compliance with infection control protocols, JCI and CBAHI standards, and to improve knowledge on preceptorship & training programs. From the pre-exam of the seven staff who participated in the nursing leadership and management program, the percentage ranges from 34% as the lowest score to 86% as the highest score. An increase in percentage that ranges from 91% to 98%, which is a significant improvement after conducting the team leadership and management skills lecture. Leadership training positively impacts all parameter scores of leadership and management skills related to nursing administration, supply and storage, infection control and safety, training and preceptorship, and National and International standards of JCI and CBAHI.