In their original setting, both spectral sequences and persistent homology are algebraic topology tools defined from filtrations of objects (e.g. topological spaces or simplicial complexes) indexed over the set Z of integer numbers. Recently, generalizations of both concepts have been proposed which originate from a different choice of the set of indices of the filtration, producing the new notions of multipersistence and spectral system. In this paper, we show that these notions are related, generalizing results valid in the case of filtrations over Z. By using this relation and some previous programs for computing spectral systems, we have developed a new module for the Kenzo system computing multipersistence. We also present a new invariant providing information on multifiltrations and applications of our algorithms to spaces of infinite type.