Effective degradation of COVID-19 related drugs by biochar-supported red mud catalyst activated persulfate process: Mechanism and pathway

Guo, Ziwei; Zhang, Yue; Gan, Shuchai; He, Huan; Cai, Nan; Xu, Jingwei; Guo, Pengran; Chen, Bin; Pan, Xuejun

doi:10.1016/j.jclepro.2022.130753

Cited by 41 publications

(5 citation statements)

References 85 publications

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“…The isotherm is a type IV isotherm, indicating the presence of mesoporous particles. Micro-mesoporous carbons usually feature H4 loops, which are closely attributed to the thin and slit-like pores (Guo et al 2022). The prominence of micropores causes the volume adsorbed to increase rapidly at lower relative pressure.…”

Section: Adsorbent Characterizationmentioning

confidence: 99%

“…Therefore, the viral infections are of the global concern. Researchers are exploring new promising antibodies, antiviral treatments, and ways to improve the efficacy of existing medications on a laboratory scale (Al-Otaibi et al 2020;Heidary et al 2021;Guo et al 2022). Antiviral drugs have received a lot of attention recently (Nannou et al 2020;Jain et al 2013;De Clercq 2004).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of acyclovir adsorption on granular activated carbon from aqueous solutions: batch and fixed-bed parametric studies

Gupta

Vyas

2023

Chem. Pap.

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The present study is aimed to assess the adsorptive potential of carbonaceous material for the acyclovir (ACVR) removal from the aquatic environment using batch and fixed-bed processes. In batch mode, the impact of various process conditions (contact time, pH, adsorbent dose, initial ACVR concentration, and temperature) on ACVR adsorption was investigated. Experimental results revealed that Langmuir isotherm and the pseudo-second-order kinetic model adequately represent the ACVR adsorption mechanism, indicating homogeneous adsorption. The process was found exothermic and spontaneous. Thermodynamic studies concluded that adsorption is a result of both physisorption and chemisorption. To understand the dynamic regime for the design of large-scale column studies, experimental data obtained from breakthrough curve were fitted to various analytical kinetic models. Yan model followed by Thomas model demonstrated a greater correlation of breakthrough data, confirming that the results are significant and are in line with Langmuir isotherm and pseudo-second-order kinetic. G-AC exhibits sufficient adsorption capacity for ACVR. Hence, it is concluded that it can be used in a fixed-bed column in continuous mode for the treatment of ACVR-contaminated wastewater.

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Section: Adsorbent Characterizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of acyclovir adsorption on granular activated carbon from aqueous solutions: batch and fixed-bed parametric studies

Gupta

Vyas

2023

Chem. Pap.

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“…•− (E = 2.5-3.1 V) also degrades CQ under acidic conditions [23]. Similarly, biomass carbon-based catalysts also effi ciently degrade CQ in a wide pH range (3-11) [24,25], and the biochar-supported red mud catalyst (RM-BC) activated persulfate process degrades CQ phosphate, HCQ sulfate, and other COVID-19 drugs [26]. Specialized activated carbon sorbents manufactured from palm kernel (Elaeis guineensis) [27] and plantain peel-activated carbon-supported zinc oxide (PPAC-ZnO) [28] possess CQ adsorption capacity.…”

Section: Introductionmentioning

confidence: 99%

Chloroquine degradation in aqueous solution under electron beam irradiation

Kabasa,

Sun,

Bułka

et al. 2024

Nukleonika

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Pharmaceutically active compounds are the most widely produced and consumed consumer products that pose a substantial threat to the environment and living organisms owing to their pharmacokinetics, side effects, and contraindications. In this study, the degradation of chloroquine (CQ), a popular antimalarial and recently proposed COVID-19 drug, was investigated under electron beam (EB) irradiation of aqueous solutions. Both the hydroxyl radical and hydrated electron generated in the radiolysis of water contribute to the degradation of CQ in aqueous solution. The overall removal efficiency for 125 mg·L-1 of the CQ solution under EB treatment is reported to be >80% at neutral pH at a maximum irradiation dose of 7 kGy. Removal efficiency is further favored by acidic and slightly alkaline conditions where reactions with hydroxyl radicals and hydrated electrons are favored, respectively. Additionally, increments in the applied dose resulted in the increased removal efficiency for the same concentration of CQ. Conversely, the removal efficiency decreased with increasing concentration of CQ at the same irradiation dose. The initial solution pH, applied irradiation dose, and initial pollutant concentration play an important role in the EB-induced degradation of CQ by influencing the available oxidizing and reducing species. The chemical oxygen demand (COD) and total organic carbon (TOC) were not significantly decreased during the treatment process and indicated the formation of organic byproducts, which were not further degraded under the current experimental conditions.

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“…Because HCQ is a potentially recalcitrant and bioaccumulative substance and is produced in large quantities, it can be passed throughout the food chain from one organism to another in various forms, increasing the menace of its occurrence in the ecosystem. This provides it high potential to be the next emerging pharmaceutical pollutant and as a result of this real problem, many researchers have developed numerous treatment methods over the past years to limit its spread in aquatic environments including photocatalysis (Kargar et al 2021;Radwan et al 2022a), electrochemical oxidation (Bensalah et al 2020b;de Araújo et al 2022), mineralization by gamma-irradiation (Boujelbane et al 2022;Jebali and Jelassi 2022), sonocatalytic degradation (Dastborhan et al 2022), Ultrasound-assisted catalytic oxidation (Ansarian et al 2022), advanced oxidation processes (Guo et al 2022;Huang et al 2022), adsorption (Bendjeffal et al 2021;Gümüş and Gümüş 2022;Picoli et al 2022). However, many of these techniques are either not very effective or too expensive, especially when applied to the treatment of large water flows.…”

Section: Introductionmentioning

confidence: 99%

“…This technique must be used upstream before wastewater and HCQ are released into natural aquatic environments. Fenton techniques are among the most promising and cost-effective methods of eliminate drugs and their derivatives from aqueous media (Neuwoehner et al 2009;Bensalah et al 2020a;Bendjeffal et al 2021;Ansarian et al 2022;Gümüş and Gümüş 2022;Guo et al 2022;Huang et al 2022;Picoli et al 2022). Recently, the Fenton method and its analogs (e.g.…”

Section: Introductionmentioning

confidence: 99%

A Box-Behnken design-based chemometric approach to optimize the degradation of hydroxychloroquine in water media using the Fe(0)/S2O2-8/UV system

Bendjeffal

Mamine

Boukachabia

et al. 2023

Preprint

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The huge utilization of hydroxychloroquine in autoimmune infections led to an abnormal increment in its concentration in wastewater, which can pose a real risk to the environment, necessitating the development of a pretreatment technique. In order to do this, we are interested in researching how hydroxychloroquine degrades in contaminated water. The main goal of this investigation is to optimize the operating conditions for the hydroxychloroquine degradation in water using Fe(0)/S2O2-8/UV system. To get adequate removal of HCQ, a chemometric method based on the Box–Behnken design was applied to optimize the influence of the empirical parameters selected including Fe(0) dose, S2O2-8 concentration, pH, and initial HCQ concentration. The quadratic regression model representing the HCQ removal rate (η%) was evolved and validated by ANOVA. The optimal conditions as a result of the above-mentioned trade-off between the four input variables, with η(%) as the dependent output variable, were captured using RSM methodology and the composite desirability function approach. For HCQ full decomposition, the optimal values of the operating factors are as follows: S2O2-8 dose: 194.309 mgL-1; Fe(0) Quantity: 198.83mgL-1 ; pH=2.017 and HCQ initial dose of 296.406mgL-1. Under these conditions, the HCQ removal rate, achieved after 60 minutes of reaction, attained 98.95%.

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Effective degradation of COVID-19 related drugs by biochar-supported red mud catalyst activated persulfate process: Mechanism and pathway

Cited by 41 publications

References 85 publications

Evaluation of acyclovir adsorption on granular activated carbon from aqueous solutions: batch and fixed-bed parametric studies

Evaluation of acyclovir adsorption on granular activated carbon from aqueous solutions: batch and fixed-bed parametric studies

Chloroquine degradation in aqueous solution under electron beam irradiation

A Box-Behnken design-based chemometric approach to optimize the degradation of hydroxychloroquine in water media using the Fe(0)/S2O2-8/UV system

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