Objectives. The aim of this study was to review the most important factors influencing women's involvement in drug trafficking. Material and methods. A systematic search of literature was carried out using Web of Science, Academic Search Complete, ProQuest Central, PsychInfo. The inclusion criteria were met by fifty-two studies. In order to facilitate the understanding of the behaviour of women who commit this crime, factor analysis was grouped into social-cultural, personal and psychological factors. Results. The main social and cultural factors considered were the adopted political system, the racial element, the cultural-regional peculiarities, the geographical positioning, the socio-economic status and the sociofamilial environment. The personal factors identified were age, occupation, lifestyle, system of norms and values, and psychological ones referred to indicators of psychological disorders, addictive behavior, the ability to control reactions and the perceived level of self-efficacy. Conclusions. The factors with the highest share of drug trafficking among women were group membership, economic and social status, educational level of parents and friends, prison history and drug use. If in the rural area the main factor that determines women to get involved in drug trafficking is the lack of a job and a low level of education, in the urban area, the influence of the group is significant. Regarding the reasons behind the involvement of women in such criminal acts or in the manifestation of addictive behaviors, these are often compensatory mechanisms, adopted in the absence of effective coping strategies. Keywords: women, drugs, trafficking, addiction, relapse.