2022
DOI: 10.1111/iwj.13879
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Effective negative pressure wound therapy for open wounds: The importance of consistent pressure delivery

Abstract: Two distinct design concepts exist for single‐use negative pressure wound therapy systems: Canister‐based versus canisterless. The canister‐based technology provides intrinsic stable delivery of the intended negative pressure, because exudate is constantly transferred from the wound into a canister, thereby preventing dressing saturation. In contrast, with a canisterless system, where delivery of the negative pressure depends on continuous evaporation of wound fluids from its dressing, loss of the intended wou… Show more

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Cited by 9 publications
(11 citation statements)
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“…Currently, the application of negative pressure suction is widely‐accepted as a good non‐surgical treatment or preoperative preparation for pressure injury 26 . With the application of negative pressure suction on wounds, a growing body of evidence has demonstrated its superiority in the aspects of improving blood flow, decreasing oedema, diminishing lateral and shear stress on wound site, and increasing lymphatic clearance 27 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Currently, the application of negative pressure suction is widely‐accepted as a good non‐surgical treatment or preoperative preparation for pressure injury 26 . With the application of negative pressure suction on wounds, a growing body of evidence has demonstrated its superiority in the aspects of improving blood flow, decreasing oedema, diminishing lateral and shear stress on wound site, and increasing lymphatic clearance 27 .…”
Section: Discussionmentioning
confidence: 99%
“…24,25 Currently, the application of negative pressure suction is widely-accepted as a good non-surgical treatment or preoperative preparation for pressure injury. 26 With the application of negative pressure suction on wounds, a growing body of evidence has demonstrated its superiority in the aspects of improving blood flow, decreasing oedema, diminishing lateral and shear stress on wound site, and increasing lymphatic clearance. 27 Significant associations with lower rates of wound complications and better efficacy have been shown in meta-analyses and reviews for negative pressure suction in wound healing of pressure injury, but outcomes vary for the treatment of the elderly, awaiting further improvements.…”
Section: Discussionmentioning
confidence: 99%
“…Excessively high pressures may lead to tissue stress concentrations in the wound bed and possible wound deterioration, by mechanically damaging an ongoing epithelialization and/or by inducing pain and psychological stress to the patient. With that said, low‐level mechano‐modulation has been shown to be linked to the stimulation of inflammatory, fibroblast migratory and fibrosis‐related tissue remodelling responses, and hence theoretically, gentle, moderate pressures on the wound bed may, in fact, contribute positively to the wound healing process 28,104,105 …”
Section: Shape Conformability Of Dressings To the Wound Bed And To Bo...mentioning
confidence: 99%
“…With that said, low-level mechano-modulation has been shown to be linked to the stimulation of inflammatory, fibroblast migratory and fibrosis-related tissue remodelling responses, and hence theoretically, gentle, moderate pressures on the wound bed may, in fact, contribute positively to the wound healing process. 28,104,105 The theory and derivation of the swelling pressure of foams in foam-based dressings are detailed in Appendix A.3. The formulation in this Appendix demonstrates that the swelling pressure of a foam-based dressing in the wound bed depends on the elapsed time post-application of the dressing and the effective diffusion coefficient of the foam, which in turn depends on the porosity and tortuosity of the foam.…”
Section: Shape Conformability Of Dressings To the Wound Bed And To Bo...mentioning
confidence: 99%
“…In addition to this inherent, key advantage in the specific context of VLUs treated by CompT, NPWT also promotes an airtight, moist wound healing environment. Such an environment induced by NPWT devices was previously shown to increase the blood flow to the wound region and reduce oedema through macro‐deformations, lower the inflammatory marker levels and remove healing inhibitors and further, mechano‐stimulate the formation of granulation tissue through promotion of tissue‐repairing cell proliferation and migration as well as angiogenesis 18–22 . Corresponding to these biological and physiological measures, patient satisfaction for treating VLUs by means of NPWT compared to traditional wound care using SOC dressings was reported to be high 23 .…”
Section: Introductionmentioning
confidence: 99%