Parity-time (PT) reversal symmetry, as a representative example in the field of non-Hermitian physics, has attracted widespread research interest in the past few years due to its extraordinary wave dynamics. PT symmetry enables unique spectral singularities including the exceptional point (EP) degeneracy where two or more eigenvalues and eigenvectors coalesce, as well as the coherent perfect absorber-laser (CPAL) point where laser and its time-reversal counterpart (i.e., coherent perfect absorber) can coexist at the same frequency. These singular points not only give rise to new physical phenomena but also provide new plausibility for building the nextgeneration sensors and detectors with unprecedented sensitivity. To date, investigations into EPs and CPAL points have unveiled their great potential in various sensing scenarios across a broad spectral range, spanning optics, photonics, electronics, and acoustics. In this review article, we will discuss ongoing developments of EP-and CPAL-based sensors composed of PT-synthetic structures and offer a glimpse into the future research directions in this emerging field.