Effective thrombolytic therapy of aortic thrombosis in the small premature infant

Richardson, Robert L.; Applebaum, Harry; Touran, Touraj; Franceschini, Ralph; Robbie, Patrick A.; Wirtschafter, David D.; Taber, Paddy

doi:10.1016/s0022-3468(88)80343-9

Cited by 21 publications

(19 citation statements)

References 8 publications

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“…Therapeutic modalities for acute bdominal aortic occlusion are embolectomy, aortobifemoral bypass, thrombolytic treatment, and axillo-bifemoral extraanatomic bypass procedures. In spite of publications that advocate thrombolytic treatment [ 11 ], we think that it may be more useful for AAO developing in the setting of a hypercoagulable state such as oral contraceptive use or factor V Leiden mutation. Treatment of AAO may vary according to the underlying etiology.…”

Section: Discussionmentioning

confidence: 92%

The Role of Extra-Anatomic Bypass in the Surgical Treatment of Acute Abdominal Aortic Occlusion

İlhan

Bozok

Ergene

et al. 2015

Korean J Thorac Cardiovasc Surg

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BackgroundAortic occlusion is rare catastophic pathology with high rates of mortality and severe morbidity. In this study, we aimed to share our experience in the management of aortic occlusion and to assess the outcomes of extra-anatomic bypass procedures.MethodsEighteen patients who had undergone extra-anatomic bypass interventions in the cardiovascular surgery department of our tertiary care center between July 2009 and May 2013 were retrospectively evaluated. All patients were preoperatively assessed with angiograms (conventional, computed tomography, or magnetic resonance angiography) and Doppler ultrasonography. Operations consisted of bilateral femoral thromboembolectomy, axillobifemoral extra-anatomic bypass and femoropopliteal bypass and were performed on an emergency basis.ResultsIn all patients during early postoperative period successful revascularization outcomes were obtained; however, one of these operated patients died on the 10th postoperative due to multiorgan failure. The patients were followed up for a mean duration of 21.2±9.4 months (range, 6 to 36 months). Amputation was not warranted for any patient during postoperative follow-up.ConclusionTo conclude, acute aortic occlusion is a rare but devastating event and is linked with substantial morbidity and mortality in spite of the recent advances in critical care and vascular surgery. Our results have shown that these hazardous outcomes may be minimized and better rates of graft patency may be achieved with extra-anatomic bypass techniques tailored according to the patient.

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Section: Discussionmentioning

confidence: 92%

The Role of Extra-Anatomic Bypass in the Surgical Treatment of Acute Abdominal Aortic Occlusion

İlhan

Bozok

Ergene

et al. 2015

Korean J Thorac Cardiovasc Surg

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“…We acknowledge that this repair was challenging and not without flaw. Richardson et al 8 described a case series of infants diagnosed with aortoiliac thromboses after UAC. In this series, all infants were treated with local infusion of intra-arterial streptokinase for 36 hours to dissolve the clot.…”

Section: Discussionmentioning

confidence: 99%

Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch

Ahle

Cardella

Cleary

et al. 2017

Journal of Vascular Surgery Cases, Innovations and Techniques

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A 43-day-old boy presented with bacteremia after umbilical artery catheterization. Duplex ultrasound examination revealed a 1.1- × 1.6-cm mycotic infrarenal aortic aneurysm and an incidental asymptomatic occluded right common iliac artery. Resection and repair were completed by creating an everted, double-layered internal jugular vein patch. Screening ultrasound examination 10 months postoperatively demonstrated successful repair.

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“…(32) A smaller dose of 50 U/kg per hour administered directly into the clot was effective in nine preterm infants who had aortoiliac thrombosis related to indwelling umbilical artery catheters. (33) UROKINASE. Urokinase, produced from primary cultures of kidney cells harvested postmortem from human neonates, has not been available in the United States since 1999, when the United States Food and Drug Administration issued a warning about manufacturing practices that had the potential risk for transmission of infectious agents.…”

Section: Thrombolytic Agentsmentioning

confidence: 99%

Management of Vascular Thrombosis and Spasm in the Newborn

Ramasethu

2005

NeoReviews

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Effective thrombolytic therapy of aortic thrombosis in the small premature infant

Cited by 21 publications

References 8 publications

The Role of Extra-Anatomic Bypass in the Surgical Treatment of Acute Abdominal Aortic Occlusion

The Role of Extra-Anatomic Bypass in the Surgical Treatment of Acute Abdominal Aortic Occlusion

Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch

Management of Vascular Thrombosis and Spasm in the Newborn

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