The primary purpose of this research was to gather information on whether overload placed upon lower extremity muscles during aerobic dance-only classes induce negative adaptations on muscular strength, endurance and, anaerobic capacity due to the inadequate strength and conditioning programs. The second purpose was to determine whether pre-season screenings of injured dancers showed drastic changes in isokinetic mean work, power, and moments before injury occurrence to identify predisposing factors compared to healthy counterparts. Ten healthy and 11 injured adolescent female ballet dancers who experienced anterior cruciate ligament injury during ballet performance participated in this study. Anthropometric measurements, anaerobic power, muscle strength and endurance performance scores were recorded using preliminary testing sessions. Significant correlations were occurred between fatigue parameters of extensor muscles and the decline in knee extension mean work, power, and moment (r=.831, p˂.001; r=.961, p˂.001; r=.969, p˂.001). Fatigue index of flexor muscles was also positively correlated with the decline in mean work, power, and moment parameters of knee flexor muscles at 1-5 to last 5 reps (r=.818, p˂.001; r=.837, p˂.001; r=.931, p˂.001), respectively. As a result, segmental musculoskeletal examinations on anaerobic power, muscle strength and endurance performance revealed that dancers performing aerobic dance only classes are prone to suffer lower extremity injuries and muscular characteristics of ankle, knee and hip muscles also predispose a decreased strength, anaerobic power and endurance performance following an anterior cruciate ligament injury.