Effectiveness and Safety of Thrombolysis in Ischemic Stroke Patients Aged 80 Years or Older

Endovascular Treatment for Acute Ischemic Stroke in Octogenarians Compared with Younger Patients: A Meta-Analysis

“…One article was excluded because it reported outcomes of patients dichotomized as > or = 75 and younger and did not provide separate data on octogenarians (8). A total of eight studies containing data on 2729 patients were included in the final analysis (9–16). The characteristics of each study including endovascular therapies used are reported in Table 1.…”

“…Two studies used the definition of parenchymal hemorrhage associated with NIHSS change of 4 or more (11,14). Two studies defined sICH as hemorrhage leading to any change in NIHSS (10,16). Finally, one study reported sICH as parenchymal hematoma associated with neurologic worsening; however, it did not define how this was measured (9).…”