Effectiveness and Utility of Mobile Device Assessment of Subjective Craving during Residential Opioid Dependence Treatment

Craving dynamics and related cerebral substrates predict timing of use in alcohol, tobacco, and cannabis use disorders

“…This finding comports with the previously highlighted link between craving instability and opioid substance use [ 21 ]. Nonetheless, we failed to observe any significant effects for the other measures of craving dynamics, namely, standard deviation – which indexes craving variability - or autocorrelation factor – which indexes craving inertia -, even though craving inertia has been linked to substance use in patients with an opioid use disorder [ 21 ] and craving variability to substance use in both opioid and tobacco use disorders [ 18 , 19 ]. It may be premature to conclude that the other indexes of craving dynamic are irrelevant, but the present findings suggest that taking variability and temporal dependency into account simultaneously using measures like MSSD allows a fine-grain, sensitive characterization of craving dynamic.…”

“…In SUD populations, a systematic review including 53 EMA studies examining the link between craving and subsequent substance use, 92 % showed that temporary craving increased the risk of substance use both concurrently and at the next sampling time [ 6 , 17 ]. Some studies using indexes of variability that did not take into account temporal stability such as SD or Mean Absolute Deviation were successful in demonstrating an impact of craving variability on substance use [ 18 , 19 ]. More recently, two studies investigated the dynamic of craving using MSSD, taking into account both variability and temporal stability: one comparing persons with or without psychotic disorders [ 20 ], and the other showing an impact on use beyond the mean level of craving in opioid use disorder [ 21 ].…”

The 24‐hour rhythm in alcohol craving and individual differences in sleep characteristics and alcohol use frequency

“…Several prior studies have reported daily rhythms (or time-of-day effects suggestive of a rhythm) in craving for various drugs of abuse, including nicotine, heroin, and other opioids (Cleveland et al, 2021;Ren et al, 2009;Teneggi et al, 2002Teneggi et al, , 2005. Furthermore, preclinical evidence has demonstrated a 24-h rhythm in alcohol consumption in alcohol-preferring mice, suggesting that both cravings and consumption of alcohol may follow a rhythm (Matson & Grahame, 2013).…”