To accurately evaluate the durability of reinforced concrete girder bridges, a durability evaluation model was developed based on the matter element extension theory, entropy weight method, and unascertained measure theory. A total of seven indicators were selected for durability evaluation: the concrete presumed strength uniformity coefficient, reinforcement corrosion potential level, chloride ion content, average value of concrete relative carbonation depth, crack width, resistivity, and characteristic value of the reinforcement protective layer thickness. The weights of the durability evaluation indices were assigned using matter element extension combined with the entropy weight method, and the multi-indicator comprehensive evaluation vector was obtained by combining the single-indicator measurement matrix. The evaluation results were analyzed by applying the confidence criterion. The results showed that the evaluation results of this model matched with the actual conditions of the girder bridges, which indicates that this durability evaluation model has good applicability and is reasonable. Finally, a comparative study proved that the model could accurately evaluate the bridge durability.