Venous thromboembolism (VTE) is one of the most common preventable disorders among hospital inpatients. Advancing age is a major risk factor for VTE. The purpose of this study was to describe and compare prevention practices and clinical outcomes in older (age 65 and older) versus younger (ages 18 to 64) hospitalized patients at risk for or diagnosed with VTE. Medical charts of 210 older and 450 younger inpatients undergoing diagnostic tests to rule out VTE were reviewed at an academic medical center. Acute VTE was diagnosed in 17.1% of older and 22.7% of younger inpatients. Pharmacological prophylaxis was used in 70% of eligible older and 57% of eligible younger inpatients. Nearly one quarter of eligible older inpatients did not receive any VTE prevention measures. The 3-month mortality was higher in older inpatients (13.9%) compared with younger inpatients (9.8%) with VTE, despite the lower rate of VTE in older inpatients. Prevention measures for VTE were underused in both older and younger inpatients.
Prevention and Clinical Outcomes in Older Inpatients with Suspected Venous ThromboembolismJung-Ah Lee, PhD, RN; and Brenda K. Zierler, PhD, RN
40Copyright © SLACK Incorporated ule on VTE prophylaxis, and evaluated the effectiveness of the tools on improving clinical and system outcomes for patients at risk for or diagnosed with VTE. The VTE Safety Toolkit consists of VTE prevention guidelines based on ACCP recommendations (Geerts et al., 2008), DVT/PE diagnostic algorithms, and treatment guidelines for acute VTE (Zierler et al., 2008). The VTE Safety Toolkit has been disseminated nationally via the AHRQ's patient safety website at http://www.ahrq.gov/qual/pips/ grants.htm. The methods of the parent study were described in detail elsewhere (Lee & Zierler, in press).During the study period from October 1, 2005 to March 31, 2006, data were reviewed on patient demographics, risk factors for VTE, use of VTE prophylaxis, and treatment of VTE for patients age 18 and older who were referred to undergo a diagnostic test to rule out VTE at an academic medical center. This study used retrospective medical chart reviews to describe the current practices on VTE prevention, treatment, and clinical outcomes in patients with suspected VTE, and particularly focused on older inpatients.The radiology electronic database at the academic medical center was used to identify patients with suspected VTE. All patients (age 18 and older) who were referred for lower extremity venous duplex ultrasonography to rule out DVT, and ventilation and perfusion scanning (V/Q scan) or computed tomographic angiography (spiral CT) to rule out PE were included in this study. Retrospective reviews of medical records for 660 consecutive hospitalized patients (age 18 and older) referred to the vascular or radiology laboratories during the study period were conducted. All inpatients suspected for VTE were classified by different age categories: older (age 65 and older) versus younger (ages 18 to 64), as well as four age categories: ages 18 to 40, 4...