Effectiveness of a New Generation Anticavity Mouthwash on Streptococcus mutans and Lactobacillus acidophilus Count: A Microbiological Study

Venkataraghavan, Karthik; Shah, Shanal

doi:10.5005/jp-journals-10015-1278

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…The comparison of antibacterial effect of 0.2% chlorohexidine, 0.05% sodium fluoride mouthwash and 2% povidone iodine mouthwash against S.mutans was previously reported and the authors concluded that 0.2% Chlorohexidine showed the maximum antibacterial effect on S. mutans which was consistent with our study result [17].…”

Section: Discussionsupporting

confidence: 92%

Antimicrobial Efficacy of Chemical and Herbal Agents against Streptococcus mutans: An in vitro study

Gulati

Bhatnagar

2018

Pesqui. bras. odontopediatria clín. integr.

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Objective: To compare and evaluate antimicrobial efficacy of chlorhexidine gluconate and fennel seeds against Streptococcus mutans. Material and Methods: Three agar petri dishes for Streptococcus mutans were prepared. The methanolic extract of fennel seed and 0.2% chlorhexidine were inoculated on the each petri dish and incubated at 37ºC for 24 hours. Zone of growth inhibition for each extract was measured in millimeters using antibiotic inhibiting zone measuring scale. Data was analyzed using SPSS statistical software. The comparison of inhibition zone against S. mutans using CHX and fennel seed extract was done using Mann-Whitney and Wilcoxon tests. All statistical analyses were set at a significance level of p<0.05. Results: The mean of zone of inhibition of S. mutans after inoculation with 0.2% chlorhexidine and fennel seed extract are 21.44 ±1.46, 15.34 ±0.74 respectively. There was statistically significant difference in the mean of inhibition zone between 0.2% chlorhexidine and fennel seed against S. mutans (p=0.047). Conclusion: Chlorhexidine and fennel seed are effective in inhibiting the growth of cariogenic bacteria. Therefore, both herbal and chemical agents can be effectively used to reduce pathogenic oral microflora.

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Section: Discussionsupporting

confidence: 92%

Antimicrobial Efficacy of Chemical and Herbal Agents against Streptococcus mutans: An in vitro study

Gulati

Bhatnagar

2018

Pesqui. bras. odontopediatria clín. integr.

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“…In agreement with our results, another in vitro study also revealed similar antibacterial and antibiofilm activities of CEO, with fewer adverse effects than CHX against Streptococcus mutans (S. mutans) and Streptococcus pyogenes [26]. Other studies tested the antibacterial effect of fennel seed methanolic extract against the cariogenic bacteria S. mutans, compared it with CHX 0.2%, and found that CHX was more effective and produced a more significant inhibition zone [27,28]. Furthermore, other researchers found that chewing the seeds for five minutes showed a rise in salivary pH that can prevent demineralization and have an anti-cariogenic property [29].…”

Section: Discussionsupporting

confidence: 90%

Extraction of Cuminum cyminum and Foeniculum vulgare Essential Oils and Their Antibacterial and Antibiofilm Activity against Clinically Isolated Porphyromonas gingivalis and Prevotella intermedia: An In Vitro Study

et al. 2023

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This study aimed to investigate the antibacterial and antibiofilm activities of the essential oils of Cuminum cyminum (CEO) and Foeniculum vulgare (FEO) on the clinically isolated Porphyromonas gingivalis (P. gingivalis) and Prevotella intermedia (P. intermedia). Subgingival plaque samples were collected from periodontal pockets (≥6 mm) of patients with generalized severe periodontitis. Microbiological and molecular tests were performed to isolate and confirm P. intermedia. A previously isolated P. gingivalis was used. The hydrodistillation method was used to extract the CEO and FEO. The antibacterial activity of the examined oils against the confirmed clinical strains was determined using the disc diffusion and broth dilution methods to determine the minimum inhibitory (MIC) and bactericidal concentrations (MBC). The antibiofilm properties of CEO and FEO were determined using the tube method. The t-test was used for comparisons of inhibition zones. Both CEO and FEO presented inhibition zones against both clinically isolated bacteria. The CEO and FEO revealed antibacterial activity with MIC values of 3.125 µL/mL and MBC of 6.25 µL/mL against P. gingivalis, respectively. In addition, their MIC and MBC against P. intermedia were 0.195 µL/mL and 3.125 µL/mL, respectively. Finally, the essential oils showed moderate to strong antibiofilm activities against the clinically isolated P. gingivalis and P. intermedia, respectively. This study supports the antibacterial and antibiofilm properties of CEO and FEO against clinically isolated P. gingivalis and P. intermedia. Further studies should focus on using these essential oils as an adjunct to periodontal therapy.

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“…Targeting Streptococcus mutans forms the most important measure for the prevention of dental caries. [4] Current methods of caries management are limited to traditional preventive approaches in combination with restorative treatments. These methods have proved inadequate to control the disease.…”

Section: Introductionmentioning

confidence: 99%

Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

Kunte¹,

Kadam²,

Patel³

et al. 2018

IDJAR

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Background: Dental caries is an infectious disease influenced by cariogenic microorganisms.Streptococcus mutans is associated with the initiation of caries, while lactobacilli with disease progression. Chlorhexidine is used as a gold standard mouthwash but with some side effects such as staining on long-term use. Nature itself is the best physician; it helps in treating oral health. Medicinal plants such as neem, tulsi, clove oil, triphala, and many more have been used in dentistry since ages to treat oral health problems such as bleeding gums, halitosis, and caries. One of them is pomegranate. It is the oldest edible fruit and considered as "a pharmacy unto itself. " Pomegranate has phenolic acids, flavonoids, and tannins in its different parts. Hydrolysable tannins called punicalagins which have free scavenging properties are the most abundant polyphenols found in pomegranate containing mouthwash. It has anticariogenic, anti-inflammatory, and antimicrobial properties. Aim: The aim of this study is to evaluate the antimicrobial efficacy of pomegranate peel extract, Hiora, and chlorhexidine. Materials and Methods: In this study, three different mouthwashes were used and divided into four groups as follows: Group A as chlorhexidine mouthwash (Hexidine), Group B as herbal mouthwash (Hiora), Group C as pomegranate peel extract 100% concentrated, and Group D as pomegranate peel extract 75% concentrated. Reference strains of S. mutans and Lactobacillus acidophilus were selected as it plays an important role in caries initiation and progression. S. mutans and Lactobacillus were grown in blood agar plates. For agar well diffusion method, wells of approximately 6-mm diameter and 4 mm in depth were made using a cork. In those wells, mouthwashes were added. Plates were incubated for 48 h at 37°C. The zone of inhibition was measured with the help of Vernier caliper. Results: The zone of inhibition of the solutions against S. Mutans and Lactobacillus shows a statistically significant P < 0.001** with f value of 1419.377 and 164.916, respectively. Conclusion: The pomegranate peel extract and Hiora show antimicrobial activities, and hence, they can be replaced for the long-term use to avoid the side effects of chlorhexidine mouthwash. Clinical significance: The pomegranate peel extract is a natural product with the antibacterial property; hence, it can be easily incorporated into oral hygiene measures such as mouthwashes or toothpastes.

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Effectiveness of a New Generation Anticavity Mouthwash on Streptococcus mutans and Lactobacillus acidophilus Count: A Microbiological Study

Abstract: Background Dental caries is one of the most widespread disease. CariFree CTx4 treatment rinse mouthwash is designed to treat the cavity-causing plaque biofilm, reduce the overpo pulation of cavity-causing bacteria, and neutralize decaycausing acids with patent-pending pH + technology.

Cited by 4 publications

References 6 publications

Antimicrobial Efficacy of Chemical and Herbal Agents against Streptococcus mutans: An in vitro study

Antimicrobial Efficacy of Chemical and Herbal Agents against Streptococcus mutans: An in vitro study

Extraction of Cuminum cyminum and Foeniculum vulgare Essential Oils and Their Antibacterial and Antibiofilm Activity against Clinically Isolated Porphyromonas gingivalis and Prevotella intermedia: An In Vitro Study

Comparative Evaluation of Antimicrobial Properties of Pomegranate Peel Extract Against Streptococcus Mutans And Lactobacillus - An In Vitro Study

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