Effectiveness of a treadmill-based aerobic exercise intervention on pain, daily functioning, and quality of life in women with primary dysmenorrhea: A randomized controlled trial

Kannan, Priya; Chapple, Cathy; Miller, Dawn; Claydon, Leica S.; Baxter, G. David

doi:10.1016/j.cct.2019.05.004

Cited by 39 publications

(45 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In contrast, previous studies [10,45] reported how the practice of certain types of sports can prevent or decrease the intensity of PD. Furthermore, exercise among women with PD has been found to enhance their quality of life [46,47].…”

Section: Discussionmentioning

confidence: 99%

Living with Restrictions. The Perspective of Nursing Students with Primary Dysmenorrhea

Fernández‐Martínez

Abreu-Sánchez

Velarde‐García

et al. 2020

IJERPH

View full text Add to dashboard Cite

Primary dysmenorrhea (PD) affects a large number of female university students, diminishing their quality of life and hindering academic performance, representing a significant cause of absenteeism. The purpose of our study was to determine how nursing students experienced restrictions as a result of primary dysmenorrhea. A qualitative exploratory study was conducted among 33 nursing students with primary dysmenorrhea. A purposeful sampling strategy was applied. Data were collected from five focus groups (two sessions each) and the field notes of 10 researchers. A video meeting platform was used to conduct the focus groups. A thematic inductive analysis was performed. Thirty-three female nursing students participated in the study with a mean age of 22.72 (SD 3.46) years. Three broad themes emerged: (a) restrictions on daily activities and sports; (b) academic restrictions, and (c) restrictions on social and sexual relationships. The students described restrictions in performing everyday activities, such as carrying weight, and shopping. Some students even gave up the practice of sports and were absent from classes at the university, and from clinical practices at the hospital. The pain affected their ability to maintain and create new social relationships. Primary dysmenorrhea caused restrictions in the personal, social and academic life of the nursing students.

show abstract

Section: Discussionmentioning

confidence: 99%

Living with Restrictions. The Perspective of Nursing Students with Primary Dysmenorrhea

Fernández‐Martínez

Abreu-Sánchez

Velarde‐García

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…However, no study has yet identified the physiological mechanisms underlying the beneficial effects of aerobic exercise-induced pain relief in primary dysmenorrhea. Our preliminary studies [14,31] identified high-intensity aerobic exercise as effective for women with primary dysmenorrhea. Our previous study to evaluate the feasibility, safety, and preliminary effectiveness of the aerobic exercise intervention on primary dysmenorrhea found large beneficial effects for a 4-week supervised treadmill-based aerobic exercise intervention on primary dysmenorrhea-associated pain quality and intensity [31].…”

Section: Introductionmentioning

confidence: 90%

“…Arachidonic acid is released from the phospholipid molecule by the lysosomal enzyme phospholipase A2 [13]. Lysosomal activity is controlled by several factors, one of which is the level of the hormone progesterone during different phases (follicular and luteal) of the menstrual cycle [3,14]. The decline in progesterone levels during the late luteal phase of the menstrual cycle labilizes the lysosomal activity resulting in greater production of arachidonic acid and consequently larger production of PGs (Figure 1) [3,14,15].…”

Section: Introductionmentioning

confidence: 99%

“…Lysosomal activity is controlled by several factors, one of which is the level of the hormone progesterone during different phases (follicular and luteal) of the menstrual cycle [3,14]. The decline in progesterone levels during the late luteal phase of the menstrual cycle labilizes the lysosomal activity resulting in greater production of arachidonic acid and consequently larger production of PGs (Figure 1) [3,14,15]. In summary, the low level of progesterone in the late luteal phase of the menstrual cycle is reported to increase the synthesis of PG, with PGs and progesterone displaying an inverse relationship [3,16].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Potential mechanisms underpinning aerobic exercise-induced analgesia in primary dysmenorrhea: a controlled non-randomized pilot trial

Kannan¹,

Cheung²,

Sheung³

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

BackgroundAerobic exercise has been shown to alleviate the pain of primary dysmenorrhea in several studies however, no study has yet identified the physiological mechanisms underlying the beneficial effects of aerobic exercise-induced pain relief in primary dysmenorrhea. The objectives of the study are: (1) To evaluate the feasibility of the protocol for a randomized controlled trial to investigate the physiological mechanisms underlying the beneficial effects of aerobic exercise on the pain associated with primary dysmenorrhea and (2) to obtain preliminary results (effect size) to estimate the sample size for the future randomized controlled trial.MethodsTwenty women aged 18–29 years were divided into two groups (high-intensity aerobic-exercise group and no-exercise control group) in a 1:1 ratio. Women assigned to the exercise group performed high-intensity treadmill-based aerobic exercise for three days a week, at 70–85% of maximum heart rate for 30 minutes for 4 weeks. The control group did not receive trial intervention but provided blood for estimation of plasma variables. Blood plasma levels of progesterone, metabolites of prostaglandin (PG) F2-alpha (13,14-dihydro-15-keto-prostaglandin F2 alpha [KDPGF2α]) and PGE2 (13,14-dihydro-15-keto-prostaglandin E2 [KDPGE2]), and tumor necrosis factor-alpha (TNF-α) were measured at 4-weeks post-intervention.ResultsWith respect to feasibility outcomes, 90% of the required number of participants were recruited in 3-4 weeks. Adherence to the intervention was 97% and the retention rate was 90%. There was an increase in progesterone levels (d = 0.36) and decreases in KDPGF2α (d = 0.35), KDPGE2 (d = 0.47), and TNF-α (d = 0.33) from baseline to week 4 in the exercise group compared with the control group.ConclusionThe study methodology appears to be feasible for conducting a full-scale randomized controlled trial. The findings indicated a trend towards an increase in progesterone levels and decreases in inflammatory pain mediators, including KDPGF2α, KDPGE2, and TNF-α, in the exercise group compared with the control group, suggesting the possibility that aerobic exercise may be effective for primary dysmenorrhea via its influence on progesterone and inflammatory pain mediators. Trial Registration Our trial is registered in the Australian New Zealand Clinical Trials Registry (ACTRN12618000784213). The date of registration is 09 May 2018. Trial registration was completed prior to enrollment of the first participant.

show abstract

“…Hypersecretion of prostaglandins, especially prostaglandin F2 alpha (PGF2a) and prostaglandin (PGF2), and increased uterine contractility will cause primary dysmenorrhea during menstruation for women 1 . Primary dysmenorrhea is menstrual pain that is felt in the absence of organic disease 2 .…”

Section: Introductionmentioning

confidence: 99%

Aerobic Exercise and Omega 3 Supplementation to Reduce Primary Dysmenorrhea (Literature Review)

Ayubi,

Sastika Putri

2021

Indian Journal of Forensic Medicine & Toxicology

View full text Add to dashboard Cite

Background: Primary dysmenorrhea is menstrual pain that is felt in the absence of organic disease. Hypersecretion of prostaglandins, especially PGF2a and PGE2 and increased uterine contractility are the main causes of primary dysmenorrhea during menstruation in women. Omega 3 can reduce menstrual pain by reducing levels of prostaglandins during menstruation. besides aerobic exercise can be done as one way to reduce the severity of primary dysmenorrhea.Methods: This study used a literature review method using comprehensive strategies such as searching for articles in research journal databases, searching through the internet, reviewing articles. The data database search used was Proquest, Pubmed, sciencediretct.com, Elsevier journal. The inclusion criteria in this study are British journals that discuss physiology, omega 3, aerobic exercise, and primary dysmenorrhea. The exclusion criteria in this study were international journals that had been published over the last 5 years in 2021.Result: Based on a review of research results, it is clear that regular aerobic exercise can significantly reduce primary dysmenorrhea due to increased progesterone. Omega 3 supplementation can significantly reduce primary dysmenorrhea because it can inhibit prostaglandin production Conclusion: Aerobic exercise and omega 3 supplementation can reduce primary dysmenorrhea during menstruation

show abstract

Effectiveness of a treadmill-based aerobic exercise intervention on pain, daily functioning, and quality of life in women with primary dysmenorrhea: A randomized controlled trial

Abstract: Ethics approval: The Health and Disability Ethics Committee of New Zealand approved this study. Ethics approval reference no.: 13/STH/206. Written informed consent was obtained from all participants prior to data collection.

Cited by 39 publications

References 35 publications

Living with Restrictions. The Perspective of Nursing Students with Primary Dysmenorrhea

Living with Restrictions. The Perspective of Nursing Students with Primary Dysmenorrhea

Potential mechanisms underpinning aerobic exercise-induced analgesia in primary dysmenorrhea: a controlled non-randomized pilot trial

Aerobic Exercise and Omega 3 Supplementation to Reduce Primary Dysmenorrhea (Literature Review)

Contact Info

Product

Resources

About