Effectiveness of a Web-Based Tailored Intervention With Virtual Assistants Promoting the Acceptability of HPV Vaccination Among Mothers of Invited Girls: Randomized Controlled Trial

Pot, Mirjam; Paulussen, Theo; Ruiter, Robert A. C.; Eekhout, Iris; Melker, Hester E. de; Spoelstra, Maxine EA; Keulen, H.M. van

doi:10.2196/jmir.7449

Cited by 50 publications

(83 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While several trials have assessed the effectiveness of interventions to increase SIV rates (especially among older people), further research is needed to determine how best to target these interventions to specific populations, depending on patient characteristics. 37 Further research is also needed to assess the effectiveness of interventions on SIV vaccination that have showed promising results for other vaccines and population groups (e.g., motivational interviewing and webbased tailored educational tools 25,38,39 ).…”

Section: Discussionmentioning

confidence: 99%

Seasonal influenza vaccination among people with diabetes: influence of patients’ characteristics and healthcare use on behavioral changes

Bocquier

Cortaredona

Fressard

et al. 2020

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

Annual seasonal influenza vaccination (SIV) is recommended for people with diabetes, but vaccine coverage remains low. We estimated the probabilities of stopping or starting SIV, their correlates, and the expected time spent in the vaccinated state over 10 seasons for different patient profiles. We set up a retrospective cohort study of patients with diabetes in 2006 (n = 16,026), identified in a representative sample of beneficiaries of the French National Health Insurance Fund. We followed them up over 10 seasons (2005/06-2015/16). We used a Markov model to estimate transition probabilities and a proportional hazards model to study covariates. Between two consecutive seasons, the probabilities of starting (0.17) or stopping (0.09) SIV were lower than those of remaining vaccinated (0.91) or unvaccinated (0.83). Men, older patients, those with type 1 diabetes, treated diabetes or more comorbidities, frequent contacts with doctors, and with any hospital stay for diabetes or influenza during the last year were more likely to start and/or less likely to stop SIV. The mean expected number of seasons with SIV uptake over 10 seasons (range: 2.6-7.9) was lowest for women <65 years with untreated diabetes and highest for men ≥65 years with type 1 diabetes. Contacts with doctors and some clinical events may play a key role in SIV adoption. Healthcare workers have a crucial role in reducing missed opportunities for SIV. The existence of empirical patient profiles with different patterns of SIV uptake should encourage their use of tailored educational approaches about SIV to address patients' vaccine hesitancy.

show abstract

Section: Discussionmentioning

confidence: 99%

Seasonal influenza vaccination among people with diabetes: influence of patients’ characteristics and healthcare use on behavioral changes

Bocquier

Cortaredona

Fressard

et al. 2020

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

show abstract

“…Results from the RCT are described in detail elsewhere ( 74 ). The main finding from the effect evaluation was that the intervention showed a significant positive effect on informed decision-making, decisional conflict, and nearly all determinants of HPV-vaccination uptake ( P < 0.001).…”

Section: Resultsmentioning

confidence: 99%

“…For example, not only did we tailor on perceived barriers (e.g., beliefs about adverse effects), like Gerend et al ( 76 ) did, but also on other beliefs (e.g., beliefs about the daughters' sexual behavior and age in relation to the need for the HPV-vaccination), attitude, subjective norms, habit, relative effectiveness, anticipated regret, risk perception, self-efficacy, and knowledge. The use of virtual assistants in interventions promoting HPV-vaccination acceptance seems promising since results from the focus groups (Step 4) and the subjective program evaluation ( 74 ) showed that mothers appreciated them very well. But, we still consider the use of virtual assistants to be complex, especially in Web-based interventions in which both spoken and written feedback/information are provided.…”

Section: Discussionmentioning

confidence: 99%

“…The intervention appeared effective in promoting HPV-vaccination acceptability and informed decision-making, and appeared to have potential for broad scale dissemination and implementation ( 74 ). This intervention blueprint will aid in interpreting the results of our evaluation studies ( 74 ). In addition, it provides insight into causal mechanisms, which contributes to theory development ( 3 , 4 , 7 – 9 ).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Systematically Developing a Web-Based Tailored Intervention Promoting HPV-Vaccination Acceptability Among Mothers of Invited Girls Using Intervention Mapping

Pot

Ruiter

Paulussen

et al. 2018

Front. Public Health

Self Cite

View full text Add to dashboard Cite

Background: Currently, the eHealth field calls for detailed descriptions of theory-based interventions in order to support improved design of such interventions. This article aims to provide a systematic description of the design rationale behind an interactive web-based tailored intervention promoting HPV-vaccination acceptability.Methods: The 6-step Intervention Mapping (IM) protocol was used to describe the design rationale. After the needs assessment in Step 1, intervention objectives were formulated in Step 2. In Step 3, we translated theoretical methods into practical applications, which were integrated into a coherent intervention in Step 4. In Step 5, we anticipated future implementation and adoption, and finally, an evaluation plan was generated in Step 6.Results: Walking through the various steps of IM resulted in a detailed description of the intervention. The needs assessment indicated HPV-vaccination uptake remaining lower than expected. Mothers play the most important role in decision-making about their daughter's immunization. However, they generally feel ambivalent after they made their decisions, and their decisions are based on rather unstable grounds. Therefore, intervention objectives were to improve HPV-vaccination uptake and informed decision-making, and to decrease decisional conflict among mothers of invited girls. Computer-tailoring was chosen as the main method; virtual assistants were chosen as a practical application to deliver interactive tailored feedback. To maximize compatibility with the needs of the target group, a user-centered design strategy by means of focus groups and online experiments was applied. In these, prototypes were tested and sequentially refined. Finally, efficacy, effectiveness, and acceptability of the intervention were tested in a randomized controlled trial. Results showed a significant positive effect of the intervention on informed decision-making, decisional conflict, and nearly all determinants of HPV-vaccination uptake (P < 0.001). Mothers evaluated the intervention as highly positive.Discussion: Using IM led to an innovative effective intervention for promoting HPV-vaccination acceptability. The intervention maps will aid in interpreting the results of our evaluation studies. Moreover, it will ease the comparison of design rationales across interventions, and may provide leads for the development of other eHealth interventions. This paper adds to the plea for systematic reporting of design rationales constituting the process of developing interventions.

show abstract

“…Information content and format may need to be tailored to the socio-cultural characteristics of patients. Factors including age, gender, and cultural background may affect the communication process and the comprehension of Informed Consent, and therefore bias the decisions taken by patients (9,10,11).…”

mentioning

confidence: 99%

Digital tools in the Informed Consent process: a systematic review

Gesualdo¹,

Palazzani

Dimitriou³

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Providing understandable information to patients is necessary to achieve the two main aims of the Informed Consent process: respecting and promoting patients’ autonomy and protecting patients from harm. In recent decades, new, primarily digital, technologies have been used to apply and test innovative formats of Informed Consent. We conducted a systematic review to explore the impact of using digital tools for Informed Consent in both clinical care and clinical trials. Understanding, comprehension, satisfaction and participation were compared for digital tools versus the traditional Informed Consent process. Methods: We searched for studies on available electronic databases, including Pubmed, ISI web of science (WoS), and Cochrane. Studies were identified using specific Mesh-terms/keywords. We included studies, published from January 2012 to April 2018, that focused on the use of digital Informed Consent tools for surgery, diagnostic procedures, therapeutic interventions, and clinical research. Digital interventions were defined as interventions that used multimedia or audio-video to provide information to patients. We classified the interventions into 3 different categories: video only, non-interactive multimedia, and interactive multimedia. Results: Our search yielded 1046 publications. After title and abstract screening 182 studies were retained for full-text analysis, of which 38 publications were included. Studies examined interactive multimedia (17/38), non-interactive multimedia (11/38), and videos (10/38), and most (34/38) studies were conducted on adults. Innovations in consent were tested for clinical/surgical procedures (26/38) and RCTs (12/38). For RCTs, 21 outcomes were explored, with a positive effect on at least one of the studied outcomes being observed in 8/12 studies. For clinical/surgical procedures 49 outcomes were explored, and 21/26 studies reported a positive effect on at least one of the studied outcomes. Conclusions: Digital technologies for informed consent were not found to affect negatively any of the outcomes, and overall, interactive multimedia tools seem desirable. Interactive multimedia tools indicated a higher impact than passive videos. Presence of a researcher may potentially enhance efficacy of different outcomes. Studies were heterogeneous in design, making evaluation of impact challenging. Robust study design including standardisation is needed to conclusively assess impact.

show abstract

Effectiveness of a Web-Based Tailored Intervention With Virtual Assistants Promoting the Acceptability of HPV Vaccination Among Mothers of Invited Girls: Randomized Controlled Trial

Cited by 50 publications

References 51 publications

Seasonal influenza vaccination among people with diabetes: influence of patients’ characteristics and healthcare use on behavioral changes

Seasonal influenza vaccination among people with diabetes: influence of patients’ characteristics and healthcare use on behavioral changes

Systematically Developing a Web-Based Tailored Intervention Promoting HPV-Vaccination Acceptability Among Mothers of Invited Girls Using Intervention Mapping

Digital tools in the Informed Consent process: a systematic review

Contact Info

Product

Resources

About