Effectiveness of Air Filters and Air Cleaners in Allergic Respiratory Diseases: A Review of the Recent Literature

Sublett, James

doi:10.1007/s11882-011-0208-5

Cited by 108 publications

(78 citation statements)

References 31 publications

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“…However, the bioaerosol levels in Danish homes can vary considerably, depending on occupancy and season Madsen et al, 2012). The association between indoor exposure to allergens and lower lung function is well known for individuals with respect to respiratory allergies or asthma (Sublett, 2011). Although our subjects did not suffer from asthma, the association between lung function and exposure to endotoxin in the home is consistent with results of previous studies on the prevalence of asthma in adults and children (Michel et al, 1996;Rabinovitch et al, 2005).…”

Section: Discussionsupporting

confidence: 89%

Cardiovascular and lung function in relation to outdoor and indoor exposure to fine and ultrafine particulate matter in middle-aged subjects

Karottki

Bekö

Clausen

et al. 2014

Environment International

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This cross-sectional study investigated the relationship between exposure to airborne indoor and outdoor particulate matter (PM) and cardiovascular and respiratory health in a population-based sample of 58 residences in Copenhagen, Denmark. Over a 2-day period indoor particle number concentrations (PNC, 10-300 nm) and PM2.5 (aerodynamic diameter<2.5 μm) were monitored for each of the residences in the living room, and outdoor PNC (10-280 nm), PM2.5 and PM10 (aerodynamic diameter<10 μm) were monitored at an urban background station in Copenhagen. In the morning, after the 2-day monitoring period, we measured microvascular function (MVF) and lung function and collected blood samples for biomarkers related to inflammation, in 78 middle-aged residents. Bacteria, endotoxin and fungi were analyzed in material from electrostatic dust fall collectors placed in the residences for 4 weeks. Data were analyzed using linear regression with the generalized estimating equation approach. Statistically significant associations were found between indoor PNC, dominated by indoor use of candles, and lower lung function, the prediabetic marker HbA1c and systemic inflammatory markers observed as changes in leukocyte differential count and expression of adhesion markers on monocytes, whereas C-reactive protein was significantly associated with indoor PM2.5. The presence of indoor endotoxin was associated with lower lung function and expression of adhesion markers on monocytes. An inverse association between outdoor PNC and MVF was also statistically significant. The study suggests that PNC in the outdoor environment may be associated with decreased MVF, while PNC, mainly driven by candle burning, and bioaerosols in the indoor environment may have a negative effect on lung function and markers of systemic inflammation and diabetes.

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Section: Discussionsupporting

confidence: 89%

Cardiovascular and lung function in relation to outdoor and indoor exposure to fine and ultrafine particulate matter in middle-aged subjects

Karottki

Bekö

Clausen

et al. 2014

Environment International

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“…One practical intervention to consider is the use of air filtration systems to reduce environmental exposures 75, 76 . A recent rostrum on air filtration published in the Journal of Allergy and Clinical Immunology outlined what is known in this field and called for more rigorous trials and research 75 .…”

Section: School-based Environmental Assessments and Interventionsmentioning

confidence: 99%

Introducing an environmental assessment and intervention program in inner-city schools

Huffaker

Phipatanakul

2014

Journal of Allergy and Clinical Immunology

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Home-based environmental interventions have demonstrated clinical benefit for children with asthma. Although much is known about school-based exposures, few studies have comprehensively examined the role the school environment plays in asthma and how effectively changing the environment may reduce morbidity, when adjusting for exposures in the home. This review summarizes the importance and common challenges of school-based environmental assessment and intervention studies linked to health effects. We focus on the key components of study development and the challenges and benefits to implementation.

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“…The benefits of PAC use for respiratory health are well-studied, with much of the literature suggesting their use in homes can improve asthma- and allergy-related symptoms [15]. Filtration efficiency of allergens may be greater because allergens tend to be larger than PM 2.5 (in the 5 to 30 μm range).…”

Section: Introductionmentioning

confidence: 99%

Portable air cleaners should be at the forefront of the public health response to landscape fire smoke

et al. 2016

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Landscape fires can produce large quantities of smoke that degrade air quality in both remote and urban communities. Smoke from these fires is a complex mixture of fine particulate matter and gases, exposure to which is associated with increased respiratory and cardiovascular morbidity and mortality. The public health response to short-lived smoke events typically advises people to remain indoors with windows and doors closed, but does not emphasize the use of portable air cleaners (PAC) to create private or public clean air shelters. High efficiency particulate air filters and electrostatic precipitators can lower indoor concentrations of fine particulate matter and improve respiratory and cardiovascular outcomes. We argue that PACs should be at the forefront of the public health response to landscape fire smoke events.

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Effectiveness of Air Filters and Air Cleaners in Allergic Respiratory Diseases: A Review of the Recent Literature

Cited by 108 publications

References 31 publications

Cardiovascular and lung function in relation to outdoor and indoor exposure to fine and ultrafine particulate matter in middle-aged subjects

Cardiovascular and lung function in relation to outdoor and indoor exposure to fine and ultrafine particulate matter in middle-aged subjects

Introducing an environmental assessment and intervention program in inner-city schools

Portable air cleaners should be at the forefront of the public health response to landscape fire smoke

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