This study was aimed at examining the relationships between the effectiveness of safety intervention programmes and implementation strategies in the Nigeria construction industry. Structured questionnaires were distributed to construction stakeholders across some selected states in Nigeria and the data generated were analysed using Pearson's product moment correlation. The study found that the effectiveness of safety intervention programmes for construction site accidents prevention is significantly related to the communication implementation strategies. Based on the principles of social ecological theory and UNICEF's communication for development strategies, this study developed a multilevel safety intervention implementation strategy for construction industries in Nigeria. Four communication strategies, namely, advocacy, social mobilisation, social change communication, and behaviour change communication, which are central to the effectiveness of safety intervention implementation programmes for construction site accidents prevention, were identified. It further revealed that these communication strategies could be individually and collectively applied at different intervention levels but that the greatest effect would be felt when all strategies are systematically combined with more efficient use of resources. The study recommended systematic actions by policy makers, construction organisations, and various community groups towards construction safety interventions, since maximum effect could only be felt when safety interventions are implemented across all levels.