Effectiveness of Bupropion Sustained Release for Smoking Cessation in a Health Care Setting

Swan, Gary E.; McAfee, Tim; Curry, Susan J.; Jack, Lisa M.; Javitz, Harold S.; Dacey, Sara; Bergman, Katherine

doi:10.1001/archinte.163.19.2337

Cited by 140 publications

(31 citation statements)

References 25 publications

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“…In nine bupropion effectiveness studies examined, subjects received extensive counselling with seven studies reporting weekly brief (15 minutes or less) face-to-face counselling from research assistants, trial nurses and counsellor/psychologists. [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] However, Australian studies have shown that smokers enrolled in smoking cessation pharmacotherapies are unlikely to actively participate in counselling. 44,45 The weight of research suggests that counselling does increase successful quit rates among smokers, therefore, if the additional expenditure is being spent on pharmacotherapies the additional marginal expenditure on telephone counselling may be money well spent.…”

Section: Discussionmentioning

confidence: 99%

“…15,21,22 Given this consensus, telephone counselling was selected as representative of counselling. 23,24 Telephone counselling has also been used with some success alongside pharmacotherapies including bupropion 25 and NRT patches 26 and is explicitly recommended in Australian treatment guidelines.…”

Section: Brief Advicementioning

confidence: 99%

“…Two studies specifi cally examined more intensive or structured psycho-social support as an adjunct to bupropion therapy for smoking cessation, with confl icting results. 25,27 Pharmacological interventions…”

Section: Varying Intensities Of Counselling With Pharmacotherapymentioning

confidence: 99%

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Cost effectiveness analysis of smoking cessation interventions

Shearer

Shanahan

2006

Australian and New Zealand Journal of Public Health

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Section: Discussionmentioning

confidence: 99%

Section: Brief Advicementioning

confidence: 99%

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Cost effectiveness analysis of smoking cessation interventions

Shearer

Shanahan

2006

Australian and New Zealand Journal of Public Health

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“…Alere is the largest provider of telephone smoking cessation interventions in the United States, currently operating QLs for 28 states and numerous large health insurers and companies. This intervention met our criteria for a comparison intervention because (a) it follows Agency for Healthcare Research and Quality (AHRQ) clinical practice guidelines for smoking cessation (Fiore et al, 2008); (b) it has demonstrated efficacy (Bush et al, 2012;Hollis et al, 2007;Swan et al, 2003); (c) its traditional CBT approach is mediated by psychological processes that are different from those of ACT, providing a rigorous test of the hypothesized mediator (Forman et al, 2007;Hayes et al, 1999); and (d) the intervention is equal in length to the ACT intervention. Sessions focus on assisting participants to develop a quit plan and teaching skills in the avoidance of triggers through techniques such as distraction, stimulus control, and changing the content of thoughts about smoking.…”

Section: Cbt Interventionmentioning

confidence: 99%

“…Interrater agreement was high and did not differ by arm (proportion of positive agreement = 0.91 for CBT; 0.99 for ACT; proportion of negative agreement = 0.00 for CBT; 0.00 for ACT). ACT calls were rated using the ACT Adherence Raters' Manual (modified from Gifford et al, 2004Gifford et al, , 2011, whereas CBT calls were rated using the Alere Call Quality Management Tool used in multiple NIH-funded trials (Bush et al, 2012;Hollis et al, 2007;Swan et al, 2003).…”

Section: Counselor Competence Ratingsmentioning

confidence: 99%

Randomized Trial of Telephone-Delivered Acceptance and Commitment Therapy Versus Cognitive Behavioral Therapy for Smoking Cessation: A Pilot Study

Bricker

Bush

Zbikowski

et al. 2014

Nicotine & Tobacco Research

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Objective: We conducted a pilot randomized trial of telephone-delivered acceptance and commitment therapy (ACT) versus cognitive behavioral therapy (CBT) for smoking cessation.Method: Participants were 121 uninsured South Carolina State Quitline callers who were adult smokers (at least 10 cigarettes/ day) and who wanted to quit within the next 30 days. Participants were randomized to 5 sessions of either ACT or CBT telephone counseling and were offered 2 weeks of nicotine replacement therapy (NRT).results: ACT participants completed more calls than CBT participants (M = 3.25 in ACT vs. 2.23 in CBT; p = .001). Regarding satisfaction, 100% of ACT participants reported their treatment was useful for quitting smoking (vs. 87% for CBT; p = .03), and 97% of ACT participants would recommend their treatment to a friend (vs. 83% for CBT; p = .06). On the primary outcome of intent-to-treat 30-day point prevalence abstinence at 6 months postrandomization, the quit rates were 31% in ACT versus 22% in CBT (odds ratio [OR] = 1.5, 95% confidence interval [CI] = 0.7-3.4). Among participants depressed at baseline (n = 47), the quit rates were 33% in ACT versus 13% in CBT (OR = 1.2, 95% CI = 1.0-1.6). Consistent with ACT's theory, among participants scoring low on acceptance of cravings at baseline (n = 57), the quit rates were 37% in ACT versus 10% in CBT (OR = 5.3, 95% CI = 1.3-22.0). Conclusions:ACT is feasible to deliver by phone, is highly acceptable to quitline callers, and shows highly promising quit rates compared with standard CBT quitline counseling. As results were limited by the pilot design (e.g., small sample), a fullscale efficacy trial is now needed.

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Effect of Bupropion Treatment on Brain Activation Induced by Cigarette-Related Cues in Smokers

Culbertson

Bramen²,

Cohen³

et al. 2011

Arch Gen Psychiatry

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Context Nicotine-dependent smokers exhibit craving and brain activation in the prefrontal and limbic regions when presented with cigarette-related cues. Bupropion hydrochloride treatment reduces cue-induced craving in cigarette smokers; however, the mechanism by which bupropion exerts this effect has not yet been described. Objective To assess changes in regional brain activation in response to cigarette-related cues from before to after treatment with bupropion (vs placebo). Design Randomized, double-blind, before-after controlled trial. Setting Academic brain imaging center. Participants Thirty nicotine-dependent smokers (paid volunteers). Interventions Participants were randomly assigned to receive 8 weeks of treatment with either bupropion or a matching placebo pill (double-blind). Main Outcome Measures Subjective cigarette craving ratings and regional brain activations (blood oxygen level-dependent response) in response to viewing cue videos. Results Bupropion-treated participants reported less craving and exhibited reduced activation in the left ventral striatum, right medial orbitofrontal cortex, and bilateral anterior cingulate cortex from before to after treatment when actively resisting craving compared with placebo-treated participants. When resisting craving, reduction in self-reported craving correlated with reduced regional brain activation in the bilateral medial orbitofrontal and left anterior cingulate cortices in all participants. Conclusions Treatment with bupropion is associated with improved ability to resist cue-induced craving and a reduction in cue-induced activation of limbic and prefrontal brain regions, while a reduction in craving, regardless of treatment type, is associated with reduced activation in prefrontal brain regions.

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Effectiveness of Bupropion Sustained Release for Smoking Cessation in a Health Care Setting

Cited by 140 publications

References 25 publications

Cost effectiveness analysis of smoking cessation interventions

Cost effectiveness analysis of smoking cessation interventions

Randomized Trial of Telephone-Delivered Acceptance and Commitment Therapy Versus Cognitive Behavioral Therapy for Smoking Cessation: A Pilot Study

Effect of Bupropion Treatment on Brain Activation Induced by Cigarette-Related Cues in Smokers

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