Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial

Lira Neto, José Cláudio Garcia; Araújo, Márcio Flávio Moura de; Araújo, Antônia Vitória Elayne Carneiro; Figueira, Joana Nágila Ribeiro; Maranhão, Thatiana Araújo; Damasceno, Marta Maria Coelho

doi:10.1590/1983-1447.2023.20230051.en

Rev. Gaúcha Enferm.

2023

DOI: 10.1590/1983-1447.2023.20230051.en

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Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial

José Cláudio Garcia Lira Neto,

Márcio Flávio Moura de Araújo,

Antônia Vitória Elayne Carneiro Araújo

et al.

Abstract: Objective: To evaluate the effectiveness of cinnamon in reducing lipid levels in people with diabetes. Method: Randomized clinical trial of parallel groups, triple-blind, conducted in Basic Health Units in the state of Piauí in 2019. People with Type 2 Diabetes Mellitus, between 18 and 80 years old, using oral antidiabetics, were included, and divided into two groups. The experimental group tested 3g of cinnamon for 90 days. Results: 140 people participated in the study. From these, the experimental group… Show more

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2024

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Cited by 2 publications

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Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial

Moreira,

Reis,

Gallassi

et al. 2024

PLoS ONE

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Introduction Contradictory claims about the efficacy of several medicinal plants to promote glycemic control in patients with type 2 diabetes mellitus (T2DM) have been explained by divergences in the administration form and by extrapolation of data obtained from healthy individuals. It is not known whether the antidiabetic effects of traditional herbal medicines are influenced by gelatin capsules. This randomized crossover trial aimed to evaluate the acute effect of a single dose of raw cinnamon consumed orally either dissolved in water as a beverage or as ordinary hard gelatin capsules on postprandial hyperglycemia (>140 mg/dL; >7.8 mmol/L) in T2DM patients elicited by a nutritionally-balanced meal providing 50 g of complex carbohydrates. Methods Fasting T2DM patients (n = 19) randomly ingested a standardized meal in five experimental sessions, one alone (Control) and the other after prior intake of 3 or 6 g of crude cinnamon in the form of hard gelatin capsules or powder dissolved in water. Blood glucose was measured at fasting and at 0.25, 0.5, 0.75, 1, 1.5 and 2 hours postprandially. After each breakfast, its palatability scores for visual appeal, smell and pleasantness of taste were assessed, as well as the taste intensity sweetness, saltiness, bitterness, sourness and creaminess. Results The intake of raw cinnamon dissolved in water, independently of the dose, decreased the meal-induced large glucose spike (peak-rise of +87 mg/dL and Δ1-hour glycemia of +79 mg/dL) and the hyperglycemic blood glucose peak. When cinnamon was taken as capsules, these anti-hyperglycemic effects were lost or significantly diminished. Raw cinnamon intake did not change time-to-peak or the 2-h post-meal glycaemia, but flattened the glycemic curve (lower iAUC) without changing the shape that is typical of T2DM patients. Conclusions This cinnamon’s antihyperglycemic action confirms its acarbose-like property to inhibit the activities of the carbohydrate-digesting enzymes α-amylases/α-glucosidases, which is in accordance with its exceptionally high content of raw insoluble fiber. The efficacy of using raw cinnamon as a diabetes treatment strategy seems to require its intake at a specific time before/concomitantly the main hyperglycemic daily meals. Trial registration: Registro Brasileiro de Ensaios Clínicos (ReBEC), number RBR-98tx28b.

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Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial

Moreira,

Reis,

Gallassi

et al. 2024

PLoS ONE

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show abstract

Avaliação Da Rotulagem De Pães De Forma Com Alegação Funcional

Araujo,

Lima,

Nascimento

et al. 2024

Rev. Contemp.

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Os rótulos contidos nos alimentos são ferramentas fundamentais para os consumidores, tendo em vista, que são responsáveis por levar informações diretas referente ao produto, auxiliando para uma melhor escolha, servindo como meio de comunicação entre fabricante e consumidor. Portanto, as alegações referentes aos ingredientes funcionais nos rótulos de pães apresentam-se como um fator decisivo na escolha do produto. Desse modo, o objetivo deste estudo foi avaliar as informações contidas nos rótulos de pães do tipo forma com alegação funcional e compará-las com a legislação vigente. A pesquisa foi realizada a partir do método de observação transversal, com amostras qualitativas não probabilísticas, onde foi analisado conteúdos como tabela nutricional, lista de ingredientes e informações declaradas nas embalagens, por meio dos rótulos que referiam a utilização de ingredientes funcionais. Todas as informações foram comparadas mediante a elaboração de um checklist contendo as resoluções vigentes relacionadas a rotulagem de alimentos. Os resultados apontaram que de 6 amostras, apenas 4 apresentavam coerência com todos os critérios estabelecidos pelos regulamentos técnicos. Visto isso, com base nos dados apresentados conclui-se, que uma parte dos pães de forma embalados e comercializados na ausência do consumidor ainda apresenta divergência quanto as informações passadas para os consumidores.

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Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial

Cited by 2 publications

References 26 publications

Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial

Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial

Avaliação Da Rotulagem De Pães De Forma Com Alegação Funcional

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