Effectiveness of coiling in the treatment of endoleaks after endovascular repair

Sheehan, Maureen K.; Barbato, Joel E.; Compton, Christopher N.; Zajko, Albert B.; Rhee, Robert Y.; Makaroun, Michel S.

doi:10.1016/j.jvs.2004.06.034

Cited by 76 publications

(56 citation statements)

References 18 publications

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“…In addition, endoleaks (at least all type I endoleaks) can be embolized through a proximal perigraft channel with catheters. 13 Moreover, for re-expansion cases of post-S/G implantation, a percutaneous puncture maneuver from the back may apply to access to the excluded aneurysmal cavity under computed tomography support without open surgery. At this point in time, judging the properties of an aneurysmal cavity by MRI is important.…”

Section: Discussionmentioning

confidence: 99%

“…2,3,9 Various methods for blocking endoleaks or endotension have been reported, such as transcatheter embolization with thrombin, lipiodol, polyurethane, glue, and coils. [12][13][14][15] Thrombin is the most commonly used method, although insufficient effects on clot formation in the sac and peripheral emboli have been reported for this method. 12 Artificial agents seem to provide favorable results for their immediate effects; however, their long-term outcomes are still of concern, because they are not physiological agents and may block the normal healing mechanism.…”

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confidence: 99%

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Development of a New Method for Endovascular Aortic Repair

Kajimoto

Shimono²,

Hirano³

et al. 2006

Circulation

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Background-Endovascular aortic repair by stent grafts (S/Gs) has been developed as a less invasive treatment for aortic aneurysms. However, some aneurysmal cavities can remain without organization, causing re-expansion. We demonstrated previously that transplantation of a cell combination (myoblasts and fibroblasts) promoted thrombus organization in a rat model. We also developed basic fibroblast growth factor (bFGF) slow-delivery S/Gs coated with elastin and impregnated with bFGF. Here, we evaluated the effects of cell transplantation combined with bFGF slow release on canine thoracic aortic aneurysmal sacs after S/Gs repair. Methods and Results-Thoracic aortic aneurysms were surgically created with jugular vein patches in 15 beagles.Myoblasts and fibroblasts of autologous skeletal muscle were isolated and cultured for cell transplantation. The S/Gs had 6 holes and produced endoleaks in the excluded cavities. Collagen gel (gel group, nϭ5) or a mixture of skeletal myoblasts and fibroblasts with collagen gel (cell group, nϭ5) were injected into the aneurysmal sacs excluded by the S/Gs. We also studied the effects of combined therapy of bFGF slow-release S/Gs and cell transplantation (hybrid group, nϭ5). After 14 days, histological analyses revealed that the excluded aneurysmal cavities of the gel group were filled with fresh thrombus, whereas the excluded cavities in the cell-transplanted groups were occupied by organized tissue. The percentages of the organized areas relative to the excluded cavities, evaluated by Masson's trichrome staining, were 18.1Ϯ4.0%, 52.6Ϯ4.0%, and 77.1Ϯ6.9% in the gel, cell, and hybrid groups, respectively. Collagen fibers had already appeared, and increased numbers of ␣-smooth muscle actin-positive cells were observed in the hybrid group. Conclusions-Cell

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Development of a New Method for Endovascular Aortic Repair

Kajimoto

Shimono²,

Hirano³

et al. 2006

Circulation

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“…16,[27][28][29][30][31] Higher failure rates with femoral TAE compared to TLE (80% vs. 8%) are believed to be due to embolization of a single vessel and failure to completely obliterate the central nidus and the feeding vessel(s) in the first attempt. Of interest, comparable success rates (72% vs. 78%) have been reported 16,32 when both the feeding artery and endoleak cavity are embolized.…”

Section: Discussion Natural History Risk Factors and Surveillance Ofmentioning

confidence: 99%

Type II Endoleak Following Endovascular Repair of Infrarenal Abdominal Aortic Aneurysm: Innovative Transgraft Approach to Contemporary Management

Jan¹,

Mewissen²

2015

Journal of Patient-Centered Research and Reviews

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Journal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality of human health, the care of the individual patient, and the care of populations. Recommended CitationJan MF, Mewissen MW. Type II endoleak following endovascular repair of infrarenal abdominal aortic aneurysm: innovative transgraft approach to contemporary management. J Patient-Centered Res Rev. 2015;2:118-126.

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“…Several techniques have been described to treat these endoleaks, including transarterial, transcaval, and translumbar approaches. [94][95][96] Type II endoleaks occur in 10% to 30% of patients after EVAR and may be associated with aneurysm growth and rupture. Subdivision of type II endoleaks into transient (resolving within 6 months) and persistent (present beyond 6 months) has been found to predict EVAR-related complications.…”

Section: April 7 2015mentioning

confidence: 99%