“…These studies employed both generic measures such as the SF 36, which assesses physical functioning, mental health, role functioning, social functioning, pain, vitality, and mobility, and disease specific measures, commonly the Functional Outcomes of Sleep Questionnaire that examines the impact of daytime sleepiness on general productivity, activity level, vigilance, social outcome, and intimate and sexual relationships, to operationally define functional status and quality of life. These studies were inconsistent in their results as to whether CPAP enhances daily functioning better than conservative measures, (26,37,41) (35) A recent study of the effect of CPAP treatment on blood pressure in non-sleepy patients, defined as an ESS < 10, whose sample included older individuals, failed to observe an effect of active treatment on blood pressure compared to sham-CPAP. (43) Previously demonstrating that CPAP positively affected blood pressure in a sample that included sleepy participants,(35) the investigators suggested that the impact of CPAP on this outcome may be mechanistically related to daytime sleepiness.…”