Effectiveness of conventional syringe irrigation, vibringe, and passive ultrasonic irrigation performed with different irrigation regimes in removing triple antibiotic paste from simulated root canal irregularities

Topçuoğlu, Hüseyin Sinan; Aktı, Ahmet; Topçuoğlu, Gamze; Düzgün, Salih; Ulusan, Özge; Akpek, Firdevs

doi:10.4103/0972-0707.186452

Cited by 10 publications

(9 citation statements)

References 27 publications

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“…The published literatures showed that it is a proper disinfectant when used as an intracanal medicament. In addition, in vivo and in vitro studies have shown that this combination of three antibiotics is effective in eliminating endodontic pathogens ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of different intra canal medicaments on the push out bond strength of endodontic sealers

Shakouie¹,

Shahi²,

Samiei³

et al. 2017

J Clin Exp Dent

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BackgroundOne of the essential properties of the root canal sealers is the adhesion to root canal dentin and their higher bond strength decreases the microleakage. The aim of the present study was to compare the effect of Different Intracanal medicaments on the push out bond strength of AH26 and MTA Fillapex sealers.Material and MethodsA total of 104 one-rooted extracted human teeth were divided into 4 (n=26) experimental groups. After the cleaning and shaping, the root canals were filled with Ca(OH)2, triantibiotic paste (TAP), Metapex or 2% chlorhexidine gel for two weeks. Then, intracanal medicaments were rinsed away and the samples in the sub-groups were obturated with gutta-percha and AH26 or MTA Fillapex sealers. After two weeks incubation, 2-mm-thick middle section of each root was then subjected to push-out testing. Data were analyzed with two-way ANOVA and LSD test.ResultsWith all the intracanal medicaments, the overall mean of bond strength values were significantly higher with AH26 compared to MTA Fillapex (p<0.05). With the use of MTA Fillapex the maximum and minimum means of bond strength values were recorded with CHX and Metapex and for AH26 were recorded with Ca(OH)2 and chlorhexidine, respectively.ConclusionsThe bond strengths of sealers to dentin are under the influence of pre-treatment with intracanal medicaments. Under the limitations of the present study, the effect of TAP on the bond strength of endodontic sealers was not negative. Key words:AH26, medicament, MTA Fillapex, push-out bond.

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Section: Introductionmentioning

confidence: 99%

Effects of different intra canal medicaments on the push out bond strength of endodontic sealers

Shakouie¹,

Shahi²,

Samiei³

et al. 2017

J Clin Exp Dent

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“…Mechanical and chemical approaches, including but not limited to endodontic files, irrigant solutions, and intracanal medicaments associated or not with emerging technologies (e.g., passive ultrasonic irrigation and photoactivated-induced passive irrigation) (7–12), have been used in both mature and immature permanent teeth. More specifically, among the presently available options, triple antibiotic paste (TAP, an equal parts mixture [1 g/mL] involving metronidazole [MET], ciprofloxacin [CIP], and minocycline [MINO]), has been recommended prior to evoke bleeding in regenerative-based procedures (13–16).…”

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confidence: 99%

Antimicrobial Efficacy of Triple Antibiotic–eluting Polymer Nanofibers against Multispecies Biofilm

Albuquerque

Nagata

Bottino

2017

Journal of Endodontics

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Introduction Elimination of microbial flora in cases of immature permanent teeth with necrotic pulp is both key and a challenging goal for the long-term success of regenerative therapy. Recent research has focused on the development of cell-friendly intracanal drug delivery systems. This in vitro study aimed to investigate the antimicrobial action of three-dimensional (3D) tubular-shaped triple antibiotic-eluting nanofibrous constructs against a multispecies biofilm on human dentin. Methods Polydioxanone (PDS) polymer solutions, antibiotic-free or incorporated with metronidazole, ciprofloxacin, and minocycline were electrospun into 3D tubular-shaped constructs. A multispecies biofilm consisting of Actinomyces naeslundii, Streptococcus sanguinis, and Enterococcus faecalis, was forced inside the dentinal tubules via centrifugation in a dentin slice in vitro model. The infected specimens were exposed to two experimental groups; i.e., 3D tubular-shaped triple antibiotic-eluting constructs and TAP, and two control groups (7-day biofilm untreated and antibiotic-free 3D tubular-shaped constructs). Biofilm elimination was quantitatively analyzed by Confocal Laser Scanning Microscopy (CLSM). Results CLSM analysis showed a dense population of viable (green) bacteria adhered to dentin and penetrated into the dentinal tubules. Upon 3D tubular-shaped triple antibiotic-eluting nanofibrous construct exposure, nearly complete elimination of viable bacteria on the dentin surface and inside the dentinal tubules was shown by the CLSM images, which was similar (p<0.05) to the bacterial death promoted by the TAP group but significantly greater when compared to both the antibiotic-free 3D tubular-shaped constructs and the control (saline). Conclusion The proposed 3D tubular-shaped antibiotic-eluting construct showed pronounced antimicrobial effects against the multispecies biofilm tested and therefore holds significant clinical potential as a disinfection strategy prior to regenerative endodontics.

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“…Therefore, a 1.5% NaOCl solution was preferred as an irrigant in this study, and it was combined with 17% EDTA. A previous study showed that combining EDTA and NaOCl could more effectively remove TAP than either NaOCl or EDTA alone, especially from the apical third of the root canal (13).…”

Section: Discussionmentioning

confidence: 98%

“…Various techniques are used for TAP removal from root canals; however, none of them can completely remove it from the root canal (10,13). The recently introduced XP-endo finisher file (XPF) (FKG Dentaire SA, La Chaux-de-Fonds, Switzerland) is a unique instrument that promises an enhanced final cleaning, even in the irregularities of root canal systems, due to its enhanced flexibility and expansion capability up to 3 mm in diameter to touch to the canal walls in threedimensions (14).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Double and Triple Antibiotic Paste Removal Efficiency of Various Irrigation Protocols

Sarıyılmaz¹,

Keskin²

2019

meandros

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Anah tar Ke li me ler İkili antibiyotik patı, üçlü antibiyotik patı, rejenaratif endodonti, irrigasyon, uzaklaştırma etkinliği Keywords Double antibiotic paste, triple antibiotic paste, regenerative endodontics, irrigation, removal efficiency Amaç: Bu çalışmanın amacı konvansiyonel şırınga irrigasyonu (KŞİ), EndoActivator (EA), pasif ultrasonik irrigasyon (PUİ), ve XP-endo finisher (XPF) ile ikili (DAP) ve üçlü (TAP) antibiyotik patlarının uzaklaştırılabilme etkinliğinin karşılaştırılması amaçlanmaktır. Gereç ve Yöntemler: Toplam 180 adet çekilmiş mandibular kanin diş kullanılmıştır. Köklerin apikal 2 mm kısmı uzaklaştırılmıştır ve unicore frezler ile apikalden koronal Öz Objective: Aim of this study was to compare the double (DAP) and triple (TAP) antibiotic paste removal efficiency of conventional syringe irrigation (CSI), EndoActivator (EA), passive ultrasonic irrigation (PUI) and XP-endo finisher (XPF) from simulated immature root canals. Materials and Methods: A total of 180 extracted mandibular canine roots were used. The apical 2 mm of the roots were removed, and Unicore drills were penetrated through the apical to the coronal direction approximately 1 mm to simulate an immature apex. Canals were prepared up to size 40 by using the Mtwo system. Roots were split longitudinally and then temporarily reassembled. The samples were randomly divided into 2 main groups as DAP and TAP. Five specimens for each main group were kept as negative control group. Then the pastes were placed with lentulo spiral. After 1 week five specimens for each main group were kept as positive control group. Then the remaining specimens in DAP and TAP groups were further assigned to 4 subgroups according to the removal technique (group 1: CSI; group 2: EA; group 3: PUI, group 4: XPF). The root halves were examined under a stereomicroscope at 10x magnification. Kruskal-Wallis H and Mann-Whitney U tests were used for statistical analyses. Results: TAP and DAP were more effectively removed by XPF and PUI compared to CSI and EA (p<0.05). XPF and PUI DAP/TAP removal effectiveness was statistically similar (p>0.05). Moreover, CSI and EA showed similar effectiveness for both paste groups (p>0.05). Regarding the type of antibiotic paste, no significant difference between TAP and DAP was found (p>0.05). Conclusion: The tested irrigation systems could not completely remove either TAP or DAP. The use of PUI or the XPF was more effective compared to the use of the EA and CSI.

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Effectiveness of conventional syringe irrigation, vibringe, and passive ultrasonic irrigation performed with different irrigation regimes in removing triple antibiotic paste from simulated root canal irregularities

Cited by 10 publications

References 27 publications

Effects of different intra canal medicaments on the push out bond strength of endodontic sealers

Effects of different intra canal medicaments on the push out bond strength of endodontic sealers

Antimicrobial Efficacy of Triple Antibiotic–eluting Polymer Nanofibers against Multispecies Biofilm

Evaluation of Double and Triple Antibiotic Paste Removal Efficiency of Various Irrigation Protocols

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