Effectiveness of Cymbopogon citratus Oil Encapsulated in Chitosan on Colletotrichum gloeosporioides Isolated from Capsicum annuum

Rivera, Adriana Patricia Tofiño; Castro-Amaris, Glorismar; Casierra–Posada, Fánor

doi:10.3390/molecules25194447

Cited by 7 publications

(3 citation statements)

References 43 publications

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“…Stapf [62]; Cymbopogon nardus (L.) Rendle [63]; Cymbopogon citratus (DC.) Stapf [64]; Hyssopus officinalis L. [65]; Pistacia atlantica Desf. [66]; Salvia officinalis L. [67]; Thymus daenensis Celak.…”

Section: Comparison With Other Nanocarriers Tested Against the Same P...mentioning

confidence: 99%

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Santiago-Aliste,

Sánchez-Hernández,

Buzón-Durán

et al. 2023

Agronomy

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Given the risks associated with synthetic fungicides, it is crucial to explore safe and sustainable alternatives. One potential solution is using bioactive natural products (BNPs). However, BNPs face challenges like lability, solubility, and lack of specificity. These issues can be addressed through nanoencapsulation. This study focuses on the evaluation of novel chitosan oligomers–hydroxyapatite–carbon nitride (COS–HAp–g-C3N4) nanocarriers (NCs) for encapsulating BNPs, specifically an extract from Uncaria tomentosa bark. The NCs were characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, and infrared spectroscopy. The NCs were monodisperse, with a mean diameter of 250 nm, and showed an encapsulation efficiency of 82%. The suitability of the loaded NCs (COS–HAp–g-C3N4–BNP, in a 2:1:0.5:1 weight ratio) for postharvest fruit protection was investigated in vitro and ex situ at a laboratory scale. Results regarding their efficacy against Botrytis cinerea on strawberries, Colletotrichum gloeosporioides on mangoes, Penicillium expansum on apples, Monilinia laxa on peaches, and Sclerotinia sclerotiorum on kiwifruit are presented. Minimum inhibitory concentrations of 250, 375, 375, 250, and 187.5 μg·mL−1 were found in vitro, respectively, while higher doses (500, 750, 750, 250, and 375 μg·mL−1, respectively) were needed to achieve effective control in postharvest tests on artificially inoculated fruit. These findings suggest that NCs containing extracts from U. tomentosa bark show promise as biorational agents and as alternatives to conventional fungicides for managing postharvest phytopathogens.

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Section: Comparison With Other Nanocarriers Tested Against the Same P...mentioning

confidence: 99%

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Santiago-Aliste,

Sánchez-Hernández,

Buzón-Durán

et al. 2023

Agronomy

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“…In the case of fungi, inhibition can be tested both in fruit and in plants, varying the environmental conditions to which the plants are subjected to the post-harvest fruits. Tofiño-Rivera et al [70], demonstrated that not only chitosan nanoparticles are effective but also microcapsules loaded with Cymbopogon citratus essential oil (CCEO) against the fungus that causes anthracnose C. gloeosporioides in topito pepper plants within 45 days of the experiment, achieving a MIC of 255 µL of CCEO inside CH microcapsules. This is due to the prolonged effect of the encapsulation.…”

Section: Vegetablesmentioning

confidence: 99%

Potential Agricultural Uses of Micro/Nano Encapsulated Chitosan: A Review

García-Carrasco,

Valdez-Baro,

Cabanillas-Bojórquez

et al. 2023

Macromol

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Chitosan is a non-toxic, biodegradable, and biocompatible natural biopolymer widely used as a nanocarrier, emulsifier, flocculant, and antimicrobial agent with potential applications in industry. Recently, chitosan has been used as an encapsulating agent for bioactive plant compounds and agrochemicals by different technologies, such as spray-drying and nanoemulsions, to enhance antimicrobial activity. Chitosan nanocomposites have been shown to increase potential biocidal, antibacterial, and antifungal activity against pathogens, presenting higher stability, decreasing degradation, and prolonging the effective concentration of these bioactive compounds. Therefore, the objective of this work is to review the most outstanding aspects of the most recent developments in the different methods of encapsulation of bioactive compounds (phenolic compounds, essential oils, among others) from plants, as well as the applications on phytopathogenic diseases (fungi and bacteria) in vitro and in vivo in cereal, fruit and vegetable crops. These perspectives could provide information for the future formulation of products with high efficacy against phytopathogenic diseases as an alternative to chemical products for sustainable agriculture.

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“…The active compound in C. citratus leaf extract works as a chemopreventive and is delivered by nano chitosan directly to the cell membrane. Apart from the demonstrated anticancer properties, C. citratus can act as an antifungal [16] and also protect normal cells through conducting oxidative stress [17]. Specifically, the active compound in C. citratus leaf extract can inhibit reduced glutathione (GSH) and activate intracellular calcium (Ca 2+ ) signals that initiate ROS-producing enzymes.…”

Section: Nano Chitosan Encapsulation Of Cymbopogon Citratus Leaf Extr...mentioning

confidence: 99%

Nano chitosan encapsulation of Cymbopogon citratus leaf extract promotes ROS induction leading to apoptosis in human squamous cells (HSC-3)

Andikoputri

Komariah

Roeslan

et al. 2021

Current Issues in Pharmacy and Medical Sciences

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World-wide, Indonesia is ranked 17th in oral cancers, with deaths reaching 2.326 cases. Of the oral cancers, 90% are squamous cell carcinoma (HSC-3). Unfortunately, conventional cancer therapy still has many ill side effects. Therefore, pharmacologists have looked for natural ingredients to prevent the growth of oral cancer cells. One source is Cymbopogon citratus leaf. Research shows that the active compound of C. citratus leaf is a chemopreventive, doing so by increasing the production of re-active oxygen species (ROS) to induce apoptosis in cancer cells. The active compound of C. citratus leaf has low stability and solubility, so it is necessary to use an encapsulation matrix such as chitosan, and modify it into smaller particles to increase its effectiveness. Purpose is determining the effect of nano chitosan encapsulation of C. citratus leaf ethanol extract (NCECC) on the reactive oxygen species of HSC-3 tongue cancer cells. This study is divided into ten groups – without treatment, doxorubicin (positive control), hydrogen peroxide, nano chitosan and C. citratus leaf extract groups, and five groups of NCECC treatment – concentrations of 100%, 75%, 50%, 25%, and 12.5%, respectively. The 100% NCECC group showed the highest ROS concentration (p<0.05), compared to 75%, 50%, 25%, 12.5% NCECC groups, and the 100% NCECC was higher than the positive control group. NCECC is effective in inducing oxidative stress on HSC-3 through increased production of ROS. Moreover, the higher the encapsulation concentration given, the greater the increase in ROS production.

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Effectiveness of Cymbopogon citratus Oil Encapsulated in Chitosan on Colletotrichum gloeosporioides Isolated from Capsicum annuum

Cited by 7 publications

References 43 publications

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Potential Agricultural Uses of Micro/Nano Encapsulated Chitosan: A Review

Nano chitosan encapsulation of Cymbopogon citratus leaf extract promotes ROS induction leading to apoptosis in human squamous cells (HSC-3)

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